Evidence map›Paper›PMID 36472789›Full record

ReviewJournal of nephrology2023

Choosing the right chronic medication for hemodialysis patients. A short ABC for the dialysis nephrologist.

Clarisse Roux, Kristelle Verollet, Julien Prouvot, Camelia Prelipcean, Emilie Pambrun, Olivier Moranne

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Clarisse RouxService Pharmacie, Hopital Universitaire de Nimes, CHU Carémeau, Nîmes, France. Clarisse.roux@chu-nimes.fr.
Kristelle VerolletService Pharmacie, Hopital Universitaire de Nimes, CHU Carémeau, Nîmes, France.
Julien ProuvotInstitut Desbrest d'Epidemiologie et Santé publique (IDESP), INSERM, Montpellier, France.
Camelia PrelipceanService Néphrologie Dialyse Apherese, Hopital Universitaire de Nimes, CHU Carémeau, Nîmes, France.
Emilie PambrunService Néphrologie Dialyse Apherese, Hopital Universitaire de Nimes, CHU Carémeau, Nîmes, France.
Olivier MoranneInstitut Desbrest d'Epidemiologie et Santé publique (IDESP), INSERM, Montpellier, France. olivier.moranne@chu-nimes.fr.ORCID http://orcid.org/0000-0002-3127-1415
Centre Hospitalier Universitaire de Nîmes · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdapting drug treatments for patients on hemodialysis with multiple chronic pathologies is a complex affair. When prescribing a medication, the risk-benefit analysis usually focuses primarily on the indication of the drug class prescribed. However, the pharmacokinetics of the chosen drug should also be taken into account. The purpose of our review was to identify the drugs to be favored in each therapeutic class, according to their safety and pharmacokinetic profiles, for the most common chronic diseases in patients on chronic hemodialysis.

methodsWe conducted a narrative review of the literature using Medline and Web of Science databases, targeting studies on the most commonly-prescribed drugs for non-communicable diseases in patients on chronic hemodialysis.

resultsThe search identified 1224 articles, 95 of which were further analyzed. The main classes of drugs included concern the cardiovascular system (anti-hypertensives, anti-arrhythmics, anti-thrombotics, hypocholesterolemics), the endocrine and metabolic pathways (anti-diabetics, gastric anti-secretory, anticoagulant, thyroid hormones, anti-gout) and psychiatric and neurological disorders (antidepressants, anxiolytics, antipsychotics and anti-epileptics).

conclusionWe report on the most often prescribed drugs for chronic pathologies in patients on chronic hemodialysis. Most of them require adaptation, and in some cases one better alternative stands out among the drug class. More pharmacokinetic data are needed to define the pharmacokinetics in the various dialysis techniques.

Indexed as

NephrologistsRenal DialysisAntidepressive AgentsHumansAntidepressive AgentsHemodialysisMedicationNon communicable chronic disease

Identifiers

PMID36472789
OpenAlexW4310773904

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.