Evidence map›Paper›PMID 36481986›Full record

ReviewBiologia futura2023

The role of post-transcriptional modifications during development.

Renáta Hamar, Máté Varga

Abstract readReview
PubMed Publisher
In one paragraph

Review in Biologia futura, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. The zebrafish (NAR genomics and bioinformatics · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Renáta HamarDepartment of Genetics, ELTE Eötvös Loránd University, Budapest, Hungary.ORCID http://orcid.org/0000-0002-0933-0810
Máté VargaDepartment of Genetics, ELTE Eötvös Loránd University, Budapest, Hungary. mvarga@ttk.elte.hu.ORCID http://orcid.org/0000-0003-4289-1705

Funding

Magyar Tudományos Akadémia János Bolyai FellowshipNational Research, Development and Innovation Office ELTE Eötvös Loránd University Institutional Excellence ProgramNemzeti Kutatási és Technológiai Hivatal FK124230
6 · The paper itself

Abstract

While the existence of post-transcriptional modifications of RNA nucleotides has been known for decades, in most RNA species the exact positions of these modifications and their physiological function have been elusive until recently. Technological advances, such as high-throughput next-generation sequencing (NGS) methods and nanopore-based mapping technologies, have made it possible to map the position of these modifications with single nucleotide accuracy, and genetic screens have uncovered the "writer", "reader" and "eraser" proteins that help to install, interpret and remove such modifications, respectively. These discoveries led to intensive research programmes with the aim of uncovering the roles of these modifications during diverse biological processes. In this review, we assess novel discoveries related to the role of post-transcriptional modifications during animal development, highlighting how these discoveries can affect multiple aspects of development from fertilization to differentiation in many species.

Indexed as

RNARNA Processing, Post-TranscriptionalAnimalsHigh-Throughput Nucleotide SequencingProteinsProteinsRNADevelopmentDiseaseEpitranscriptomeRNA modification

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.