Evidence map›Paper›PMID 36484235›Full record

Trial reportPediatric obesity2023

An addiction-based digital weight loss intervention: A multi-centre randomized controlled trial.

Alaina P Vidmar, Sarah J Salvy, Choo Phei Wee, Robert Pretlow, D Steven Fox, Jennifer K Yee, Cambria Garell, Suzette Glasner, Steven D Mittelman

Open access · greenAbstract readRandomized Controlled TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Pediatric obesity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Management of Childhood Obesity.International journal of molecular sciences · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Alaina P VidmarDepartment of Pediatrics, Center for Endocrinology, Diabetes and Metabolism, Children's Hospital Los Angeles and Keck School of Medicine of USC, Los Angeles, California, USA.ORCID 0000-0003-3790-6255
Sarah J SalvyDepartment of Medicine, Cedars-Sinai Medical Center, Research Center for Health Equity Samuel Oschin Comprehensive Cancer Institute, Los Angeles, California, USA.ORCID 0000-0002-8202-182X
Choo Phei WeeDepartment of Population and Public Health Sciences, Keck School of Medicine of USC, Southern California Clinical Science Institute, Los Angeles, California, USA.
Robert PretloweHealth International, Seattle, Washington, USA.
D Steven FoxDepartment of Pharmaceutical and Health Economics, School of Pharmacy of the University of Southern California, Los Angeles, California, USA.
Jennifer K YeeDivision of Pediatric Endocrinology, Harbor-UCLA Medical Center, Harbor-UCLA Medical Center, Torrance, California, United States.
Cambria GarellDepartment of Pediatrics, Division of General Pediatrics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Suzette GlasnerDepartment of Psychiatry & Biobehavioral Sciences, University of California, Los Angeles, California, USA.
Steven D MittelmanDepartment of Pediatrics, Division of General Pediatrics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
University of California, Los Angeles · USCedars-Sinai Medical Center · USChildren's Hospital of Los Angeles · USClinical Science Institute · USeHealth Initiative · USHarbor–UCLA Medical Center · USUniversity of Southern California · US

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Southern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0M
Evaluating environmental control (AVOID) and inhibitory control (RESIST) strategies to improve weight management outcomesR01DK130851 · NIDDK · CEDARS-SINAI MEDICAL CENTER · PI Sarah-Jeanne Salvy · 2022 to 2026
$3.5M
NCATS NIH HHS UL1 TR000130NCATS NIH HHS UL1 TR001855NIDDK NIH HHS R01 DK130851
6 · The paper itself

Abstract

objectiveThis randomized clinical trial tested the effectiveness of an addiction-based digital weight-loss intervention, focusing on withdrawal/abstinence from self-identified problem foods, snacking and excessive amounts at meals, and discomfort displacement, with and without coaching, compared to an in-person, multi-disciplinary, care model among adolescents with obesity. We hypothesized that the digital intervention with coaching would yield greater weight loss and lower delivery burden than the standard clinical arm, and greater participant engagement than the digital arm without coaching.

methodsAdolescents were randomized to app intervention, with or without coaching, or in-person multidisciplinary obesity intervention for 6 months. The primary outcome was change in %BMI

resultsAll adolescents (n = 161; BMI ≥95th%, age 16 ± 2.5 year; 47% Hispanic, 65% female, 59% publicly insured) lost weight over 24-weeks (-1.29%, [-1.82, -0.76], p < 0.0001), with no significant weight loss difference between groups (p = 0.3). Girls lost more weight than boys, whereas binge eating behaviour at baseline was associated with increase in %BMI

conclusionsContrary with our hypothesis, our results showed no difference in the change in BMI status between treatment arms. Since efficacy of this digital intervention was not inferior to in-person, multi-disciplinary care, this could offer a reasonable weight management option for clinicians, based on youth and family specific characteristics, such as accessibility, resources, and communication styles. CLINICAL

trial registrationClinicalTrials.gov identifier: NCT035008353.

Indexed as

Behavior, AddictiveWeight LossAdolescentEthnicityFemaleFoodHumansMaleObesitybinge eating disordercoachingdigital healthexecutive functioningfood addictionobesitypaediatricsweight loss

Identifiers

PMID36484235
PMCPMC9905275
OpenAlexW4311574035

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.