Evidence map›Paper›PMID 36484722›Full record

ArticleJournal of rehabilitation medicine2022

Feasibility and Safety of a Powered Exoskeleton for Balance Training for People Living with Multiple Sclerosis: A Single-Group Preliminary Study (Rapper III).

Mohamed Sakel, Karen Saunders, Philip Hodgson, David Stephensen, Chetan P Phadke, Paul A Bassett, David Wilkinson

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of rehabilitation medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06429085 (Rex Robot Assisted Rehabilitation to Enhance Balance and Mobility for People With Multiple Sclerosis, Clinical and Biomarker Study - RAPPER IV), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06429085 phase1completednot on this map

Rex Robot Assisted Rehabilitation to Enhance Balance and Mobility for People With Multiple Sclerosis, Clinical and Biomarker Study - RAPPER IV

TypeinterventionalSponsorEast Kent Hospitals University NHS Foundation TrustRan2018 to 2020Enrolled20ConditionsMultiple SclerosisArmsRex robotic assisted balance exercises
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Mohamed SakelConsultant Physician in Neuro-rehabilitation Medicine, Director of East Kent Neuro-rehabilitation Service, East Kent Hospitals University Foundation NHS Trust, Canterbury, Kent.
Karen SaundersSchool of Social Policy, Sociology and Social Research, University of Kent, Canterbury. kss31@kent.ac.uk.
Philip HodgsonPhysiotherapy Department, Tees, Esk and Wear Valleys NHS Foundation Trust, Durham.
David StephensenPhysiotherapy Department, East Kent Hospitals University Foundation NHS Trust, Canterbury, UK.
Chetan P PhadkeWest Park Healthcare Centre, Toronto, Ontario, Canada.
Paul A BassettStatsconsultancy Ltd, Buckinghamshire, UK.
David WilkinsonSchool of Psychology, University of Kent, Canterbury, Kent, UK.
East Kent Hospitals University NHS Foundation Trust · GBUniversity of Kent · GBTees, Esk and Wear Valleys NHS Foundation Trust · GBWest Park Healthcare Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the feasibility, usability, safety, and potential health benefits of using an exoskeleton device for rehabilitation of people living with multiple sclerosis.

designSingle-group preliminary study. SUBJECTS: Eleven adults living with multiple sclerosis, with Expanded Disability Status Scores that ranged from 6 to 7.5 (mean age (standard deviation; SD) 54.2 (11.8) years), were recruited.

methodsIndividual participants undertook a balance rehabilitation exercise programme using the Rex Rehab robotic exoskeleton device. Each participant undertook 4 × 45-60 min supervised, balance exercise sessions. Primary outcomes were: (i) the number of participants who completed the trial protocol safely, and (ii) the number and nature of adverse events reported. Secondary outcomes were: mobility; balance; spasticity; sleep; functional independence; quality of life; and device satisfaction.

resultsTen out of 11 participants completed the trial protocol safely. Four adverse events were recorded (1 serious), all of which were deemed unrelated to the trial. Secondary outcomes showed allied improvements in balance, joint mobility, spasticity and quality of life. All participants found the device acceptable to use.

conclusionThese results suggest that it is feasible and safe to use the Rex Rehab exoskeleton device to assist with balance rehabilitation for people living with multiple sclerosis.

Indexed as

Exoskeleton DeviceMultiple SclerosisRoboticsAdultExercise TherapyFeasibility StudiesHumansMuscle SpasticityQuality of Life

Identifiers

PMID36484722
PMCPMC9774743
OpenAlexW4311674924

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.