Evidence map›Paper›PMID 36494348›Full record

ArticleNature communications2022

Selective posttranslational inhibition of Ca

Travis J Morgenstern, Neha Nirwan, Erick O Hernández-Ochoa, Hugo Bibollet, Papiya Choudhury, Yianni D Laloudakis, Manu Ben Johny, Roger A Bannister, Martin F Schneider, Daniel L Minor and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Modulating ion channels with nanobodies.Synthetic and systems biotechnology · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Travis J MorgensternDepartment of Molecular Pharmacology and Therapeutics, Columbia University Irving Medical Center, New York, NY, USA.
Neha NirwanCardiovascular Research Institute, University of California, San Francisco, CA, USA.
Erick O Hernández-OchoaDepartment of Biochemistry and Biology, University of Maryland School of Medicine, Baltimore, MD, USA.
Hugo BibolletDepartment of Biochemistry and Biology, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-7020-586X
Papiya ChoudhuryDepartment of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY, USA.
Yianni D LaloudakisVagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA.
Manu Ben JohnyDepartment of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-5645-0815
Roger A BannisterDepartment of Biochemistry and Biology, University of Maryland School of Medicine, Baltimore, MD, USA.
Martin F SchneiderDepartment of Biochemistry and Biology, University of Maryland School of Medicine, Baltimore, MD, USA.
Daniel L MinorCardiovascular Research Institute, University of California, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-5998-4214
Henry M ColecraftDepartment of Molecular Pharmacology and Therapeutics, Columbia University Irving Medical Center, New York, NY, USA. hc2405@cumc.columbia.edu.ORCID http://orcid.org/0000-0002-2340-8899
Columbia University Irving Medical Center · USUniversity of Maryland, Baltimore · USColumbia University · USQB3 · USUniversity of California, San Francisco · US

Funding

Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Anil K Rustgi · 1985 to 2026
$115.3M
Structure and function of voltage-gated calcium channelsR01HL080050 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DANIEL L MINOR · 2005 to 2026
$9.8M
L-type channel trafficking and modulation in heartR01HL121253 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Henry M. Colecraft, Steven O Marx · 2014 to 2026
$8.4M
Mechanisms of Long QT Syndrome 1 in HeartR01HL122421 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI COLECRAFT, HENRY M. · 2016 to 2019
$1.8M
Rad and amyotrophic lateral sclerosis (ALS)R01NS103777 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI HERNANDEZ-OCHOA, ERICK OMAR · 2018 to 2022
$1.7M
Voltage sensor domain movements in skeletal muscle fiber activationR01AR075726 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI WARD, CHRISTOPHER WILLIAM · 2021 to 2025
$1.7M
Becton Dickinson LSR II Analytical Flow CytometerS10RR027050 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CLYNES, RAPHAEL A. · 2011 to 2011
$413k
Engineering Nanobodies To Study Beta Subunit-Specific Voltage-Gated Calcium Channel Complexes in Pancreatic Beta CellsF31DK118866 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MORGENSTERN, TRAVIS JAMES · 2018 to 2020
$135k
NCI NIH HHS P30 CA013696NCRR NIH HHS S10 RR027050NHLBI NIH HHS R01 HL080050NHLBI NIH HHS R01 HL121253NHLBI NIH HHS R01 HL122421NIAMS NIH HHS R01 AR075726NIDDK NIH HHS F31 DK118866NINDS NIH HHS R01 NS103777
6 · The paper itself

Abstract

Ca

Indexed as

Calcium ChannelsMyocytes, CardiacCalciumCalcium Channels, L-TypeNeuronsProtein Isoformssrc Homology DomainsCalciumCalcium ChannelsCalcium Channels, L-TypeProtein Isoforms

Identifiers

PMID36494348
PMCPMC9734117
OpenAlexW4311679898

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.