Evidence map›Paper›PMID 36497343›Full record

ReviewCancers2022

MiR-101: An Important Regulator of Gene Expression and Tumor Ecosystem.

Ning Liu, Chunsheng Yang, Ang Gao, Meili Sun, Deguan Lv

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. The role of microRNAs in calcific aortic valve disease.Frontiers in cardiovascular medicine · 2025
    Review
  16. Article
  17. Article
  18. The Expression Patterns and Implications ofInternational journal of molecular sciences · 2023
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ning LiuDepartment of Oncology, Central Hospital Affiliated to Shandong First Medical University, Jinan 250013, China.
Chunsheng YangDepartment of Oncology, Central Hospital Affiliated to Shandong First Medical University, Jinan 250013, China.
Ang GaoDepartment of Oncology, Central Hospital Affiliated to Shandong First Medical University, Jinan 250013, China.
Meili SunDepartment of Oncology, Central Hospital Affiliated to Shandong First Medical University, Jinan 250013, China.
Deguan LvUPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15232, USA.ORCID 0000-0003-3142-9814
Jinan Central Hospital · CNUPMC Hillman Cancer Center · US

Funding

Youth Project of Natural Science Foundation of Shandong Province ZR2020QH21
6 · The paper itself

Abstract

MiRNAs are small single-stranded non-coding RNAs. MiRNA contributes to the transcriptional and post-transcriptional regulation of mRNA in different cell types, including mRNA transcription inhibition and mRNA decay and phenotypes via the effect of several essential oncogenic processes and tumor microenvironment. MiR-101 is a highly conserved miRNA that was found to alter the expression in various human cancers. MiR-101 has been reported to have tumor oncogenic and suppressive effects to regulate tumorigenesis and tumor progression. In this review, we summarize the new findings about the roles of miR-101 in cancers and the underlying mechanisms of targeting genes degradation and microenvironment regulation, which will improve biological understanding and design of novel therapeutics.

Indexed as

apoptosisinvasionmicroenvironmentmigrationmiR-101proliferationsuppressortherapy

Identifiers

PMID36497343
PMCPMC9739992
OpenAlexW4310071655

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.