ArticleJournal of clinical medicine2022
Traumatic Brain Injury and Acute Kidney Injury-Outcomes and Associated Risk Factors.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Brain-kidney cross-talk: A call for action!World journal of critical care medicine · 2026Article
- Association between serum glucose/potassium ratio and acute kidney injury in patients with traumatic brain injury: based on MIMIC-IV database.Journal of global health · 2026Article
- Serum antithrombin III level predicts acute kidney injury in patients with traumatic brain injury.Experimental and therapeutic medicine · 2026Article
- Comparative machine learning to predict acute kidney injury in traumatic brain injury: a MIMIC-IV cohort with SHAP interpretation.Frontiers in medicine · 2026Article
- Acute kidney injury in critically ill patients with traumatic brain injury: A single-center retrospective cohort study.World journal of critical care medicine · 2025Article
- A Single-Center Review of Renal Replacement Therapy in Patients With Acute Traumatic Brain Injury.Cureus · 2025Article
- Effect of Creatinine on Various Clinical Outcomes in Patients with Severe Traumatic Brain Injury (TBI).Metabolites · 2025Article
- Impact of mannitol on mortality in patients with non-traumatic intracerebral haemorrhage and acute kidney injury: a retrospective study.Scientific reports · 2025Article
- Incidence and predictors of acute kidney injury among traumatic brain injury patients in Northwest Ethiopia: a cohort study using survival analysis.BMC nephrology · 2025Article
- Acute Kidney Injury Secondary to Trauma Brain Injury (TBI) and the Role of Angiotensin-1-7.Advanced biomedical research · 2025Article
- A nomogram for predicting early mortality in patients with traumatic brain injury requiring mechanical ventilation based on clinical laboratory data.Scientific reports · 2024Article
- Racial/Ethnic and Geographic Disparities in Comorbid Traumatic Brain Injury-Renal Failure in US Veterans and Associated Veterans Affairs Resource Costs, 2000-2020.Journal of racial and ethnic health disparities · 2024Article
- Acute kidney injury in neurocritical care.Critical care (London, England) · 2023Review
- Chronic kidney disease as a predictive factor for poor prognosis in traumatic brain injury among older adults: a case-control study.Frontiers in neurology · 2023Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our objective was to analyze the contribution of acute kidney injury (AKI) to the mortality of isolated TBI patients and its associated risk factors. Observational, prospective and multicenter registry (RETRAUCI) methods were used, from March 2015 to December 2019. Isolated TBI was defined as abbreviated injury scale (AIS) ≥ 3 head with no additional score ≥ 3. A comparison of groups was conducted using the Wilcoxon test, chi-square test or Fisher's exact test, as appropriate. A multiple logistic regression analysis was conducted to analyze associated risk factors in the development of AKI. For the result, overall, 2964 (30.2%) had AIS head ≥ 3 with no other area with AIS ≥ 3. The mean age was 54.7 (SD 19.5) years, 76% were men, and the ground-level falls was 49.1%. The mean ISS was 18.4 (SD 8). The in-hospital mortality was 22.2%. Up to 310 patients (10.6%) developed AKI, which was associated with increased mortality (39% vs. 17%, adjusted OR 2.2). Associated risk factors (odds ratio (OR) (95% confidence interval)) were age (OR 1.02 (1.01-1.02)), hemodynamic instability (OR 2.87 to OR 5.83 (1.79-13.1)), rhabdomyolysis (OR 2.94 (1.69-5.11)), trauma-associated coagulopathy (OR 1.67 (1.05-2.66)) and transfusion of packed red-blood-cell concentrates (OR 1.76 (1.12-2.76)). In conclusion, AKI occurred in 10.6% of isolated TBI patients and was associated with increased mortality.
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