Evidence map›Paper›PMID 36499348›Full record

ArticleInternational journal of molecular sciences2022

Snapshot into the Type-2-Diabetes-Associated Microbiome of a Romanian Cohort.

Gratiela Gradisteanu Pircalabioru, Mariana-Carmen Chifiriuc, Ariana Picu, Laura Madalina Petcu, Maria Trandafir, Octavian Savu

Open access · goldFull text read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Gratiela Gradisteanu PircalabioruResearch Institute of University of Bucharest (ICUB), 050095 Bucharest, Romania.
Mariana-Carmen ChifiriucResearch Institute of University of Bucharest (ICUB), 050095 Bucharest, Romania.ORCID 0000-0001-6098-1857
Ariana Picu"N.C. Paulescu" National Institute of Diabetes, Nutrition and Metabolic Diseases, 020042 Bucharest, Romania.
Laura Madalina Petcu"N.C. Paulescu" National Institute of Diabetes, Nutrition and Metabolic Diseases, 020042 Bucharest, Romania.
Maria TrandafirDepartment of Doctoral School, "Carol Davila" University of Medicine and Pharmacy, 5th District, 050474 Bucharest, Romania.
Octavian Savu"N.C. Paulescu" National Institute of Diabetes, Nutrition and Metabolic Diseases, 020042 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROUniversity of Bucharest · RO

Funding

AOSR Teams 288/20.02.2022.Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii C1.2.PFE-CDI.2021-587Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii CNFIS-FDI-2022- 0675.Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-III-P1-1.1-36PD-2019-0499, Grant number 224/2021
6 · The paper itself

Abstract

The prevalence of type 2 diabetes mellitus (T2D) is alarmingly increasing worldwide, urgently calling for a better understanding of the underlying mechanisms in order to step up prevention and improve therapeutic approaches. It is becoming evident that the gut microbiota seem to have an endless capacity to impact T2D. In this study, we profile the gut microbiome patterns in T2D patients from Romania, by using quantitative Real-Time PCR and next generation sequencing. We enrolled a total of 150 individuals (105 T2D patients, 50 of them without metformin treatment and 45 healthy volunteers). The levels of potentially beneficial butyrate-producing bacteria were significantly reduced, while potentially pathogenic microorganisms such as

Indexed as

Diabetes Mellitus, Type 2Gastrointestinal MicrobiomeMetforminMicrobiotaBacteroidetesHumansMetformindiabeteshypertensionmetabolic diseasemetabolitesmicrobiomemicrobiota

Identifiers

PMID36499348
PMCPMC9741184
OpenAlexW4310479602

What Socratic holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.