Evidence map›Paper›PMID 36500282›Full record

ArticleMolecules (Basel, Switzerland)2022

Isolation and In Silico Prediction of Potential Drug-like Compounds with a New Dimeric Prenylated Quinolone Alkaloid from

Fatema Tuz Zohora, A T M Zafrul Azam, Sinthyia Ahmed, Khondaker Miraz Rahman, Mohammad A Halim, Md Rafi Anwar, Md Hossain Sohrab, Fatema Tabassum, Choudhury Mahmood Hasan, Monira Ahsan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Fatema Tuz ZohoraDepartment of Pharmaceutical Chemistry, University of Dhaka, Dhaka 1000, Bangladesh.ORCID 0000-0002-6087-0425
A T M Zafrul AzamDepartment of Pharmaceutical Chemistry, University of Dhaka, Dhaka 1000, Bangladesh.
Sinthyia AhmedDivision of Computer Aided Drug Design, The Red-Green Research Centre, BICCB, Tejgaon, Dhaka 1219, Bangladesh.
Khondaker Miraz RahmanSchool of Cancer and Pharmaceutical Science, King's College London, 150 Stamford Street, London SE1 9NH, UK.ORCID 0000-0001-8566-8648
Mohammad A HalimDepartment of Chemistry and Biochemistry, Kennesaw State University, Kennesaw, GA 30144, USA.
Md Rafi AnwarCollege of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71201, USA.ORCID 0000-0003-4576-906X
Md Hossain SohrabBangladesh Council of Scientific and Industrial Research (BCSIR), Dr. Qudrat-E-Khuda Road, Dhaka 1205, Bangladesh.ORCID 0000-0002-8314-2594
Fatema TabassumDepartment of Pharmaceutical Chemistry, University of Dhaka, Dhaka 1000, Bangladesh.
Choudhury Mahmood HasanDepartment of Pharmaceutical Chemistry, University of Dhaka, Dhaka 1000, Bangladesh.
Monira AhsanDepartment of Pharmaceutical Chemistry, University of Dhaka, Dhaka 1000, Bangladesh.
University of Dhaka · BDBangladesh Council of Scientific and Industrial Research · BDGreen University of Bangladesh · BDKennesaw State University · USKing's College London · GBUniversity of Louisiana at Monroe · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new dimeric prenylated quinolone alkaloid, named 2,11-didemethoxy-vepridimerine A, was isolated from the root bark of

Indexed as

AlkaloidsAntineoplastic AgentsCOVID-19QuinolonesZanthoxylumMolecular Docking SimulationMolecular Dynamics SimulationPolymersProtease InhibitorsSARS-CoV-2AlkaloidsAntineoplastic AgentsPolymersProtease InhibitorsQuinolones2,11-didemethoxy-vepridimerine A2-quinolonebenzophenanthridine alkaloidsSARS-CoV-2 (Mpro)Zanthoxylum rhetsa

Identifiers

PMID36500282
PMCPMC9737416
OpenAlexW4309935856

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.