Evidence map›Paper›PMID 36502155›Full record

ArticleSensors (Basel, Switzerland)2022

Assessing Cerebellar Disorders with Wearable Inertial Sensor Data Using Time-Frequency and Autoregressive Hidden Markov Model Approaches.

Karin C Knudson, Anoopum S Gupta

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Sensitive Quantification of Cerebellar Speech Abnormalities Using Deep Learning Models.IEEE access : practical innovations, open solutions · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Karin C KnudsonData Intensive Studies Center, Tufts University, Medford, MA 02155, USA.ORCID 0000-0003-1312-6473
Anoopum S GuptaDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-8741-0621

Funding

A Computational Approach for Quantifying Motor Behaviors in Spinocerebellar Ataxias to Improve Early Detection of Motor Signs and Precisely Estimate Disease Severity and Disease ChangeR01NS117826 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI GUPTA, ANOOPUM SATYAWAN · 2021 to 2025
$2.7M
Ataxia-Telangiectasia Children's Project NABiogen (United States) NANIH HHS R01NS117826NINDS NIH HHS R01 NS117826
6 · The paper itself

Abstract

Wearable sensor data is relatively easily collected and provides direct measurements of movement that can be used to develop useful behavioral biomarkers. Sensitive and specific behavioral biomarkers for neurodegenerative diseases are critical to supporting early detection, drug development efforts, and targeted treatments. In this paper, we use autoregressive hidden Markov models and a time-frequency approach to create meaningful quantitative descriptions of behavioral characteristics of cerebellar ataxias from wearable inertial sensor data gathered during movement. We create a flexible and descriptive set of features derived from accelerometer and gyroscope data collected from wearable sensors worn while participants perform clinical assessment tasks, and use these data to estimate disease status and severity. A short period of data collection (<5 min) yields enough information to effectively separate patients with ataxia from healthy controls with very high accuracy, to separate ataxia from other neurodegenerative diseases such as Parkinson’s disease, and to provide estimates of disease severity.

Indexed as

Cerebellar DiseasesParkinson DiseaseWearable Electronic DevicesAtaxiaHumansMovementataxiaBayesian nonparametricshidden Markov modelsIMUstime-frequency analysiswaveletswearable sensors

Identifiers

PMID36502155
PMCPMC9737930

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.