Evidence map›Paper›PMID 36505294›Full record

ArticleAmerican journal of translational research2022

Association of dyslipidemia and hypoxemia in patients with obstructive sleep apnea hypopnea syndrome: a cross-sectional study.

Zhitao Fan, Liping Dong, Xiaopei Wang, Jinqiao Zhang, Tong Qiao, Jihua Zhang, Jie Zhang, Dongmei Song

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zhitao FanClinical Biobank, The First Hospital of Hebei Medical University Shijiazhuang, Hebei, China.
Liping DongClinical Biobank, The First Hospital of Hebei Medical University Shijiazhuang, Hebei, China.
Xiaopei WangClinical Biobank, The First Hospital of Hebei Medical University Shijiazhuang, Hebei, China.
Jinqiao ZhangClinical Biobank, The First Hospital of Hebei Medical University Shijiazhuang, Hebei, China.
Tong QiaoClinical Biobank, The First Hospital of Hebei Medical University Shijiazhuang, Hebei, China.
Jihua ZhangDepartment of Otolaryngology, The First Hospital of Hebei Medical University Shijiazhuang, Hebei, China.
Jie ZhangClinical Biobank, The First Hospital of Hebei Medical University Shijiazhuang, Hebei, China.
Dongmei SongClinical Biobank, The First Hospital of Hebei Medical University Shijiazhuang, Hebei, China.
Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveStudies have shown that dyslipidemia may contribute to chronic tissue hypoxia. However, it remains unclear whether dyslipidemia affects chronic hypoxia in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). Therefore, from a clinical practice perspective, the purpose of this study was to investigate the effect of dyslipidemia on chronic hypoxia in OSAHS patients.

methodIn athis cross-sectional survey, 320 consecutive OSAHS patients were enrolled. By screening under different conditions, 211 patients were finally enrolled in the study. Patients were grouped according to apnea-hypopnea index (AHI), into a mild-to-moderate (AHI < 30) group and severe OSAHS group (AHI ≥ 30).

resultsComparative analysis shows that 45% of mild-to-moderate OSAHS patients had severe hypoxemia. Univariate and multivariate regression analyses showed that AHI, triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C) had independent effects on

conclusionThe results of this study indicate that abnormalities in TG and HDL-C, in addition to upper airway obstruction, are among the factors that aggravate chronic hypoxia in tissues from OSAHS patients.

Indexed as

cross-sectional studydyslipidemiahypoxemiaObstructive sleep apnea hypopnea syndrome

Identifiers

PMID36505294
PMCPMC9730063
OpenAlexW4311285715

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.