Evidence map›Paper›PMID 36506087›Full record

ReviewFrontiers in cell and developmental biology2022

Matricellular proteins in cutaneous wound healing.

Claudia Griselda Cárdenas-León, Kristina Mäemets-Allas, Mariliis Klaas, Heli Lagus, Esko Kankuri, Viljar Jaks

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Advances in pharmacological and pharmaceutical sciences · 2025
    Article
  14. Sea lice (Frontiers in genetics · 2025
    Article
  15. Review
  16. Matricellular proteins: Potential biomarkers in head and neck cancer.Journal of cell communication and signaling · 2024
    Review
  17. Review
  18. Matricellular Proteins in the Homeostasis, Regeneration, and Aging of Skin.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Claudia Griselda Cárdenas-LeónDepartment of Cell Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
Kristina Mäemets-AllasDepartment of Cell Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
Mariliis KlaasDepartment of Cell Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
Heli LagusDepartment of Plastic Surgery and Wound Healing Centre, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Esko KankuriDepartment of Pharmacology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Viljar JaksDepartment of Cell Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
University of Tartu · EEUniversity of Helsinki · FITartu University Hospital · EE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous wound healing is a complex process that encompasses alterations in all aspects of the skin including the extracellular matrix (ECM). ECM consist of large structural proteins such as collagens and elastin as well as smaller proteins with mainly regulative properties called matricellular proteins. Matricellular proteins bind to structural proteins and their functions include but are not limited to interaction with cell surface receptors, cytokines, or protease and evoking a cellular response. The signaling initiated by matricellular proteins modulates differentiation and proliferation of cells having an impact on the tissue regeneration. In this review we give an overview of the matricellular proteins that have been found to be involved in cutaneous wound healing and summarize the information known to date about their functions in this process.

Indexed as

extracellular matrixnon-structural matrix proteinsre-epithelializationregenerationSkin

Identifiers

PMID36506087
PMCPMC9730256
OpenAlexW4309848552

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.