Evidence map›Paper›PMID 36506461›Full record

ArticleVaccine: X2022

Humoral and T-cell mediated response after administration of mRNA vaccine BNT162b2 in frail populations.

Roberta Campagna, Laura Mazzuti, Giuliana Guerrizio, Chiara Nonne, Giuseppe Migliara, Corrado De Vito, Ivano Mezzaroma, Sabina Chiaretti, Caterina Fimiani, Valentina Pistolesi and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccine: X, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Roberta CampagnaDepartment of Molecular Medicine Sapienza University of Rome, Viale dell'Università, 33, 000185 Rome, Italy.
Laura MazzutiDepartment of Molecular Medicine Sapienza University of Rome, Viale dell'Università, 33, 000185 Rome, Italy.
Giuliana GuerrizioDepartment of Molecular Medicine Sapienza University of Rome, Viale dell'Università, 33, 000185 Rome, Italy.
Chiara NonneDepartment of Molecular Medicine Sapienza University of Rome, Viale dell'Università, 33, 000185 Rome, Italy.
Giuseppe MigliaraDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Piazzale Aldo Moro, 5, 00185 Rome, Italy.
Corrado De VitoDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Piazzale Aldo Moro, 5, 00185 Rome, Italy.
Ivano MezzaromaDepartment of Translational and Precision Medicine, Sapienza University of Rome, Viale dell'Università, 37, 00185 Rome, Italy.
Sabina ChiarettiDepartment of Translational and Precision Medicine, Sapienza University of Rome, Viale dell'Università, 37, 00185 Rome, Italy.
Caterina FimianiDepartment of Internal Medicine, Endocrine-Metabolic Sciences and Infectious Disease, Policlinico Umberto I, 155, 00161, Italy.
Valentina PistolesiDepartment of Internal Medicine and Medical Specialties Sapienza University of Rome, Policlinico, 155, 00161 Rome, Italy.
Santo MorabitoDepartment of Internal Medicine and Medical Specialties Sapienza University of Rome, Policlinico, 155, 00161 Rome, Italy.
Ombretta TurrizianiDepartment of Molecular Medicine Sapienza University of Rome, Viale dell'Università, 33, 000185 Rome, Italy.
Sapienza University of Rome · ITPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with frailty are considered to be at greater risk to get severe infection from SARS-CoV-2. One of the most effective strategies is vaccination. In our study we evaluated both the humoral immune response elicited by the vaccination at different time points, and the

Indexed as

HemodialysisHIVHumoral responseSARS-CoV-2T-cell responseVaccine

Identifiers

PMID36506461
PMCPMC9721197
OpenAlexW4311761917

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.