Evidence map›Paper›PMID 36508052›Full record

ArticleJournal of cell communication and signaling2023

Catalpol inhibits hepatic stellate cell activation by reducing the formation and changing the contents of hepatocyte-derived extracellular vesicles.

Zheng-Yuan Xie, Heng-Wei Cao, Qing Wang, Hui Lu, Wen Du

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cell communication and signaling, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zheng-Yuan XieDepartment of Gastroenterology, The Second Affiliated Hospital of Nanchang University, No.1 Mingde Road, Nanchang, 330006, Jiangxi Province, People's Republic of China. xzyxzy1230@163.com.
Heng-Wei CaoMedical College of Nanchang University, Nanchang, Jiangxi, China.
Qing WangMedical College of Nanchang University, Nanchang, Jiangxi, China.
Hui LuMedical College of Nanchang University, Nanchang, Jiangxi, China.
Wen DuMedical College of Nanchang University, Nanchang, Jiangxi, China.
Nanchang University · CNSecond Affiliated Hospital of Nanchang University · CN

Funding

Key Program of Natural Science Foundation of Jiangxi Province of China Grant No. 20212ACB206017Key Research and Development Program of Jiangxi Provincial Department of Science and Technology Grant No. 20203BBG73044National Natural Science Foundation of China Grant No. 81860119Science and Technology Project Foundation of Education Department of Jiangxi Province, China Grant No. GJJ200193
6 · The paper itself

Abstract

Hepatic stellate cell (HSC) activation is the central event in hepatic fibrosis. The cross-talk between HSCs and hepatocytes, which is mediated by extracellular vesicles (EVs), affects HSC activation. This study aimed to investigate whether Catalpol (CTP) attenuated hepatic fibrosis via modulating EVs. Mice were injected intraperitoneally with CCl

Indexed as

Autophagosome-autolysosome fusionAutophagyCatalpolExtracellular vesiclesHepatic fibrosis

Identifiers

PMID36508052
PMCPMC10409968
OpenAlexW4311204748

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.