Evidence map›Paper›PMID 36510041›Full record

ArticleInternational urology and nephrology2023

Evaluation of malnutrition and inflammation after total parathyroidectomy in patients on maintenance dialysis.

Xiaochun Zhou, Yuke Kong, Zhigang Ma, Tianxi Liu, Tingxin Wan, Wenjun Zhang, Pengming Zhao, Ya Wang, Li Ma, Gouqin Wang and 8 more

Abstract read
PubMed Publisher
In one paragraph

Article in International urology and nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Xiaochun ZhouLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Yuke KongLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Zhigang MaDepartment of Nephrology, Gansu Provincial People's Hospital, Lanzhou, 730030, Gansu, China.
Tianxi LiuDepartment of Nephrology, Lanzhou University First Hospital, Lanzhou, 730030, Gansu, China.
Tingxin WanDepartment of Nephrology, Wuwei People's Hospital of Gansu Province, Wuwei, 730030, Gansu, China.
Wenjun ZhangLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Pengming ZhaoLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Ya WangLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Li MaLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Gouqin WangLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Xiaoling WangLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Yaojun LiangLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Xuan DuLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Yaxian NingLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Rongrong DengLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Ya TangLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Weiwei HuLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Jianqin WangLaboratory Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China. wangjianqin@medmail.com.cn.
Lanzhou University · CNLanzhou University Second Hospital · CNFirst Hospital of Lanzhou University · CNGansu Provincial Hospital · CNHuawei Technologies (China) · CN

Funding

Gansu Longyuan young talents innovation and entrepreneurship No. 2020RCXM127Lanzhou Chengguan District Science and Technology Bureau talent innovation and entrepreneurship No. 2021RCCX0027the Clinical Medical Research Center of Gansu Province 21JR7RA436
6 · The paper itself

Abstract

purposeTo evaluate the effect of total parathyroidectomy (tPTx) on malnutrition and inflammation in patients on maintenance dialysis (MHD) having secondary hyperparathyroidism (SHPT).

methodsTwenty-five patients on MHD having SHPT who were being treated with tPTx were selected, and changes in their general condition (dry body mass), parathyroid hormone (PTH) and calcium levels, nutrition state (hemoglobin, hematocrit, serum albumin, and total iron binding capacity), and inflammatory status [serum C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor (TNF-α), and the malnutrition-inflammation score (MIS)] were observed at 12, 24, and 36 months postoperatively.

resultsCompared with the preoperative period, the dry body mass increased at 12, 24, and 36 months postoperatively (P < 0.01), hemoglobin, hematocrit, and serum albumin increased significantly (P < 0.01), whereas calcium, phosphorus, and PTH levels decreased significantly (P < 0.01). Serum CRP, IL-6, and TNF-α levels were significantly decreased at 12, 24, and 36 months after surgery (P < 0.01). Furthermore, MIS was reduced as well but to a lesser extent (P < 0.01).

conclusiontPTx effectively reduced MIS in maintenance dialysis patients, and the alleviated malnutrition and improved inflammatory status may contributed to improving the quality of life of patients on MHD with SHPT.

Indexed as

Hyperparathyroidism, SecondaryKidney Failure, ChronicMalnutritionCalciumC-Reactive ProteinHemoglobinsHumansInflammationInterleukin-6ParathyroidectomyParathyroid HormoneQuality of LifeRenal DialysisSerum AlbuminTumor Necrosis Factor-alphaCalciumC-Reactive ProteinHemoglobinsInterleukin-6Parathyroid HormoneSerum AlbuminTumor Necrosis Factor-alphaInflammationMaintenance hemodialysisMalnutritionSecondary hyperparathyroidismTotal parathyroidectomy

Identifiers

PMID36510041
OpenAlexW4311182358

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.