Evidence map›Paper›PMID 36511653›Full record

ReviewJournal of internal medicine2023

Global guidance for the recognition, diagnosis, and management of tumor-induced osteomalacia.

Suzanne M Jan de Beur, Salvatore Minisola, Wei-Bo Xia, Bo Abrahamsen, Jean-Jacques Body, Maria Luisa Brandi, Roderick Clifton-Bligh, Michael Collins, Pablo Florenzano, Pascal Houillier and 5 more

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of internal medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 2 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Multimodal Functional Imaging in Tumor-induced Osteomalacia:Molecular imaging and radionuclide therapy · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Beyond DOTATATE: [European journal of nuclear medicine and molecular imaging · 2026
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. A nomogram for predicting surgery outcome of tumor-induced osteomalacia: a case-control study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 15 institutions in 12 countries.

Suzanne M Jan de BeurDivision of Endocrinology and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Salvatore MinisolaDepartment of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University, Rome, Italy.
Wei-Bo XiaDepartment of Endocrinology, Key Laboratory of Endocrinology, State Key Laboratory of Complex Severe and Rare Diseases, NHC, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Bo AbrahamsenOpen Patient data Explorative Network (OPEN), Department of Clinical Research, University of Southern Denmark and Odense University Hospital, Odense, Denmark.
Jean-Jacques BodyDepartment of Medicine, CHU Brugmann, Université Libre de Bruxelles, Brussels, Belgium.
Maria Luisa BrandiDepartment of Surgery and Translational Medicine, University of Florence, University Hospital of Florence, Florence, Italy.
Roderick Clifton-BlighDepartment of Endocrinology and Diabetes, Royal North Shore Hospital, Sydney, Australia.
Michael CollinsSkeletal Diseases and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA.
Pablo FlorenzanoCentro Traslacional de Endocrinología UC (CETREN-UC), Endocrinology Department, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Pascal HouillierCentre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université de Paris, Département des Maladies Rénales et Métaboliques, Hôpital Européen Georges-Pompidou, Assistance Publique-Hôpitaux de Paris, Paris, France.
Yasuo ImanishiDepartment of Metabolism, Endocrinology, and Molecular Medicine, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Erik A ImelDivision of Endocrinology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Aliya A KhanDivision of Endocrinology and Metabolism, Calcium Disorders Clinic, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
M Carola ZillikensDepartment of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Seiji FukumotoFujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan.
Cancer Institute of New South Wales · AUCentre de Recherche des Cordeliers · FRCentre Hospitalier Universitaire Brugmann · BEChinese Academy of Medical Sciences & Peking Union Medical College · CNErasmus MC · NLIndiana University – Purdue University Indianapolis · USJohns Hopkins Medicine · USMcMaster University · CANational Institutes of Health · USOdense University Hospital · DKOsaka Metropolitan UniversityPontificia Universidad Católica de Chile · CLSapienza University of Rome · ITTokushima University · JPUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by mesenchymal tumors that secrete fibroblast growth factor 23 (FGF23). Patients present with progressive bone pain, muscle weakness, and fragility fractures. TIO is characterized by hypophosphatemia, excess renal phosphate excretion, and low/inappropriately normal 1,25-dihydroxyvitamin D (1,25(OH)

Indexed as

Fractures, BoneHypophosphatemiaParaneoplastic SyndromesFibroblast Growth FactorsHumansOsteomalaciaPainPhosphatesFibroblast Growth FactorsPhosphatesconsensusdiagnostic tests/routinefibroblast growth factor 23hypophosphatemiareferral and consultationtumor-induced osteomalacia

Identifiers

PMID36511653
PMCPMC10108006
OpenAlexW4311279646

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.