Evidence map›Paper›PMID 36514764›Full record

ReviewFood science & nutrition2022

Can soy isoflavones in combination with soy protein change serum concentration of adiponectin and resistin? A systematic review and meta-analysis on randomized clinical trials.

Mitra Hariri, Bahareh Amirkalali, Ensiyeh Mollanoroozy, Ali Gholami

Abstract readReview
In one paragraph

Review in Food science & nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mitra HaririNoncommunicable Diseases Research Center Neyshabur University of Medical Sciences Neyshabur Iran.ORCID https://orcid.org/0000-0002-5370-2140
Bahareh AmirkalaliGastrointestinal & Liver Diseases Research Center Iran University of Medical Sciences Tehran Iran.
Ensiyeh MollanoroozyNoncommunicable Diseases Research Center Neyshabur University of Medical Sciences Neyshabur Iran.
Ali GholamiNoncommunicable Diseases Research Center Neyshabur University of Medical Sciences Neyshabur Iran.ORCID https://orcid.org/0000-0003-0338-9368

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some studies proposed the anti-inflammatory effect of soy protein and soy isoflavones by changing the serum adiponectin and resistin levels. The purpose of this research was to determine the impact of soy isoflavones and soy protein on blood adiponectin and resistin levels in adults. Scopus, PubMed, Cochrane Library, ISI Web of Science, and ClinicalTrials.gov databases were searched until April 2022. The effect size was computed by the mean changes from the beginning for intervention and comparison groups and their standard deviation. In the case of significant heterogeneity, DerSimonian and Laird random-effects model was used. Six and five clinical trials were selected for the systematic review and meta-analysis, respectively. The overall estimate indicated that soy isoflavones in combination with soy protein did not significantly change serum adiponectin level (weighted mean differences (WMD) = 0.36 μg/ml; 95% confidence interval (CI): -0.26, 0.99;

Indexed as

adiponectinmeta‐analysisresistinsoy isoflavonessoy proteinsystematic review

Identifiers

PMID36514764
PMCPMC9731533

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.