Evidence map›Paper›PMID 36518247›Full record

ArticleFrontiers in endocrinology2022

Epididymal epithelial degeneration and lipid metabolism impairment account for male infertility in occludin knockout mice.

Bao Ying Liu, Bao Li Zhang, Da Yuan Gao, Qing Li, Xin Yu Xu, Winnie Shum

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Metabolomic Analysis of Cauda Epididymal Fluid in Yaks and Cattle.Animals : an open access journal from MDPI · 2025
    Article
  5. Article
  6. Review
  7. Research Progress in Skin Aging, Metabolism, and Related Products.International journal of molecular sciences · 2023
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Bao Ying LiuSchool of Life Science and Technology, Shanghai Tech University, Shanghai, China.
Bao Li ZhangSchool of Life Science and Technology, Shanghai Tech University, Shanghai, China.
Da Yuan GaoSchool of Life Science and Technology, Shanghai Tech University, Shanghai, China.
Qing LiCenter for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.
Xin Yu XuSchool of Life Science and Technology, Shanghai Tech University, Shanghai, China.
Winnie ShumSchool of Life Science and Technology, Shanghai Tech University, Shanghai, China.
Chinese Academy of Sciences · CNCenter for Excellence in Molecular Cell Science · CNFudan University · CNShanghaiTech University · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Occludin (OCLN) is a tight junction protein and Ocln deletion mutation causes male infertility in mice. However, the role of OCLN in male reproductive system remains unknown. In this study, we used an interdisciplinary approach to elucidate the underlying mechanism of male infertility in related to OCLN function, including

Indexed as

EpididymisInfertility, MaleOccludinAnimalsArachidonic AcidsLipid MetabolismMaleMiceMice, KnockoutSemenSperm MotilityArachidonic AcidsOccludinOcln protein, mousearachidonic acidepididymislipid metabolismluminal acidificationoccludinV-ATPase

Identifiers

PMID36518247
PMCPMC9742356
OpenAlexW4310264663

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.