Evidence map›Paper›PMID 36521347›Full record

ArticleEnvironment international2023

Time-lagged relationships between a decade of air pollution exposure and first hospitalization with Alzheimer's disease and related dementias.

Daniel Mork, Danielle Braun, Antonella Zanobetti

Abstract read
In one paragraph

Article in Environment international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  15. Air pollution amyloidogenesis is attenuated by the gamma-secretase modulator GSM-15606.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel MorkDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: dmork@hsph.harvard.edu.
Danielle BraunDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA.
Antonella ZanobettiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Brent Andrew Coull · 1985 to 2026
$44.6M
National Cohort Studies of Alzheimer's Disease, Related Dementias and Air PollutionR01AG066793 · NIA · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI ZANOBETTI, ANTONELLA · 2020 to 2025
$4.2M
The confluence of extreme heat cold on the health and longevity of an Aging Population with Alzheimers and related DementiaRF1AG074372 · NIA · HARVARD MEDICAL SCHOOL · PI DOMINICI, FRANCESCA, ESTIRI, HOSSEIN · 2022 to 2023
$2.6M
NIA NIH HHS R01 AG066793NIA NIH HHS RF1 AG074372NIEHS NIH HHS P30 ES000002
6 · The paper itself

Abstract

Alzheimer's disease and related dementias (ADRD) poses substantial health challenges among an aging population. One of the primary challenges in studying ADRD is that biological processes underlying these ailments begin decades prior to diagnosis. Previous studies indicate a relationship between ADRD and air pollution exposure to both fine particulate matter (PM

Indexed as

Air PollutantsAir PollutionAlzheimer DiseaseAgedEnvironmental ExposureHospitalizationHumansMedicareNitrogen DioxideParticulate MatterRetrospective StudiesUnited StatesAir PollutantsNitrogen DioxideParticulate Matter

Identifiers

PMID36521347
PMCPMC9885762

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.