Evidence map›Paper›PMID 36527621›Full record

ArticleAdvances in experimental medicine and biology2022

Pulmonary Embolism in COVID-19 Patients Is Not Related to a Deterioration of Tissue Oxygenation.

Sebastiano Cicco, F Albanese, R Didonna, A Magistro, A Vacca, C Cariddi, G Lauletta, F Pappagallo, A G Solimando, R Ria

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Article in Advances in experimental medicine and biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sebastiano CiccoCOVID Section, Unit of Internal Medicine "Guido Baccelli", Department of Biomedical Sciences and Human Oncology, University of Bari, University Hospital Policlinico di Bari, Bari, Italy.
F AlbaneseCOVID Section, Unit of Internal Medicine "Guido Baccelli", Department of Biomedical Sciences and Human Oncology, University of Bari, University Hospital Policlinico di Bari, Bari, Italy.
R DidonnaCOVID Section, Unit of Internal Medicine "Guido Baccelli", Department of Biomedical Sciences and Human Oncology, University of Bari, University Hospital Policlinico di Bari, Bari, Italy.
A MagistroCOVID Section, Unit of Internal Medicine "Guido Baccelli", Department of Biomedical Sciences and Human Oncology, University of Bari, University Hospital Policlinico di Bari, Bari, Italy.
A VaccaDivision of Internal Medicine, Department of Medicine, Building 8, University of Udine, Udine (UD), Italy.
C CariddiDipartimento dell'Emergenza e Trapianti d'Organo (DETO), Sezione di Anestesiologia e Rianimazione, Ospedale Policlinico, University of Bari Aldo Moro, Bari, Italy.
G LaulettaCOVID Section, Unit of Internal Medicine "Guido Baccelli", Department of Biomedical Sciences and Human Oncology, University of Bari, University Hospital Policlinico di Bari, Bari, Italy.
F PappagalloCOVID Section, Unit of Internal Medicine "Guido Baccelli", Department of Biomedical Sciences and Human Oncology, University of Bari, University Hospital Policlinico di Bari, Bari, Italy.
A G SolimandoCOVID Section, Unit of Internal Medicine "Guido Baccelli", Department of Biomedical Sciences and Human Oncology, University of Bari, University Hospital Policlinico di Bari, Bari, Italy.
R RiaCOVID Section, Unit of Internal Medicine "Guido Baccelli", Department of Biomedical Sciences and Human Oncology, University of Bari, University Hospital Policlinico di Bari, Bari, Italy.
University of Bari Aldo Moro · ITUniversity of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 induces robust systemic inflammation. One of the main complications is the increased coagulation due to endotheliitis. There is an increased incidence of pulmonary embolism (PE) in COVID-19 patients. However, clinical characteristics for a strict analysis are yet to be determined.

aimWe evaluated oxygenation and characteristics in patients with COVID-19 PE (CPE). MATERIAL AND

methodsWe evaluated 215 COVID-19 patients from 1 January to 30 April 2021. We found 18 patients affected by PE (CPE, 50.0% males, aged 67.00 ± 10.86 years). As controls, we used data from patients affected by PE evaluated in our ward between 1 January 2015 and 31 December 2019 (64 patients, 53.1% males, aged 70.88 ± 16.44 years). All patients underwent a complete physical examination, pulmonary computerised tomography, laboratory tests, D-dimers and blood gas analysis at the time of diagnosis.

resultsThere were no differences in laboratory tests nor in D-dimers between the two groups. In the CPE group we found a significantly increased pO DISCUSSION: COVID-19 PE appears to have a different clinical setting. Reduced oxygenation described in PE may not to be considered as a sign of disease. The increased A-aDO

Indexed as

COVID-19Pulmonary EmbolismThrombosisFemaleHumansMaleOxygenRetrospective StudiesOxygenEndotheliitisPlatelet countsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV2)Systemic inflammation

Identifiers

PMID36527621
OpenAlexW4312018305

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.