Evidence map›Paper›PMID 36528839›Full record

ReviewHuman cell2023

Roles of RNA-binding proteins in neurological disorders, COVID-19, and cancer.

Daniel Ruben Akiola Sanya, Claudia Cava, Djamila Onésime

Open access · bronzeAbstract readReview
In one paragraph

Review in Human cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 32 citations in OpenAlex.

  1. The roles of RNA-binding proteins in ovarian aging.Journal of assisted reproduction and genetics · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. RBPs: an RNA editor's choice.Frontiers in molecular biosciences · 2024
    Review
  9. 2'-Frontiers in molecular biosciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Daniel Ruben Akiola SanyaINRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, 78350, Jouy-en-Josas, France. sanyadaniel86@yahoo.com.ORCID http://orcid.org/0000-0001-9493-3669
Claudia CavaInstitute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Segrate, 20131, Milan, Italy.
Djamila OnésimeINRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, 78350, Jouy-en-Josas, France.
AgroParisTech · FRInstitute of Molecular Bioimaging and Physiology · ITUniversité Paris-Saclay · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA-binding proteins (RBPs) have emerged as important players in multiple biological processes including transcription regulation, splicing, R-loop homeostasis, DNA rearrangement, miRNA function, biogenesis, and ribosome biogenesis. A large number of RBPs had already been identified by different approaches in various organisms and exhibited regulatory functions on RNAs' fate. RBPs can either directly or indirectly interact with their target RNAs or mRNAs to assume a key biological function whose outcome may trigger disease or normal biological events. They also exert distinct functions related to their canonical and non-canonical forms. This review summarizes the current understanding of a wide range of RBPs' functions and highlights their emerging roles in the regulation of diverse pathways, different physiological processes, and their molecular links with diseases. Various types of diseases, encompassing colorectal carcinoma, non-small cell lung carcinoma, amyotrophic lateral sclerosis, and Severe acute respiratory syndrome coronavirus 2, aberrantly express RBPs. We also highlight some recent advances in the field that could prompt the development of RBPs-based therapeutic interventions.

Indexed as

COVID-19MicroRNAsNeoplasmsNervous System DiseasesHumansRNA-Binding ProteinsMicroRNAsRNA-Binding ProteinsCancerNeurodegenerative diseasesPost-transcriptional gene regulationRNARNA-binding proteinsRNA processingViral infection

Identifiers

PMID36528839
PMCPMC9760055
OpenAlexW4311843027

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.