Evidence map›Paper›PMID 36531709›Full record

ArticleFrontiers in cardiovascular medicine2022

Alterations of sympathetic dynamics after atrial fibrillation ablation by analysis sympathetic nerve activity provide prognostic value for recurrence and mechanistic insights into ablation.

Jien-Jiun Chen, Chen Lin, Yuan-Cheng Chuang, Shu-Fang Lee, Tse-Yu Lin, Chieh-Cheh Yu, Chia-Ti Tsai, Min-Tsun Liao, Tin-Tse Lin, Lian-Yu Lin and 1 more

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Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jien-Jiun ChenDivision of Cardiology, Department of Internal Medicine, Yunlin Branch of National Taiwan University Hospital, Douliu, Taiwan.
Chen LinDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, Taiwan.
Yuan-Cheng ChuangDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, Taiwan.
Shu-Fang LeeDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, Taiwan.
Tse-Yu LinDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, Taiwan.
Chieh-Cheh YuDivision of Cardiology, Department of Internal Medicine, College of Medicine, National Taiwan University and Hospital, Taipei, Taiwan.
Chia-Ti TsaiDivision of Cardiology, Department of Internal Medicine, College of Medicine, National Taiwan University and Hospital, Taipei, Taiwan.
Min-Tsun LiaoDivision of Cardiology, Department of Internal Medicine, Hsinchu Branch of National Taiwan University Hospital, Hsinchu, Taiwan.
Tin-Tse LinDivision of Cardiology, Department of Internal Medicine, College of Medicine, National Taiwan University and Hospital, Taipei, Taiwan.
Lian-Yu LinDivision of Cardiology, Department of Internal Medicine, College of Medicine, National Taiwan University and Hospital, Taipei, Taiwan.
Men-Tzung LoDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary vein isolation (PVI) is the cornerstone of atrial fibrillation (AF) ablation. Success is associated with autonomic function modulation; however, the relationship between the changes after ablation is not fully understood. We aimed to investigate the effect of ablation on autonomic modulation by skin sympathetic nerve activity (SKNA) using conventional electrocardiogram (ECG) electrodes and to predict the treatment success. Methods: We enrolled 79 patients. We recorded neuECG for 10 min at 10 kHz before and after ablation. The NeuECG was bandpass-filtered (500-1,000 Hz) and integrated at intervals of 100 ms (iSKNA). iSKNA was averaged over different time windows (1-, 5-,10-s; aSKNAs), and burst analyses were derived from aSKNAs to quantify the dynamics of sympathetic activities. AF recurrence after 3 months was defined as the study endpoint. Results: Sixteen patients experienced AF recurrence after the ablation. For burst analysis of 1-s aSKNA, the recurrence group had a higher bursting frequency than the non-recurrence group (0.074 ± 0.055 vs. 0.109 ± 0.067; Conclusion: We demonstrated the applicability of neuECG for determining sympathetic modulation during AF ablation. Decreasing sympathetic activity is the key to successful ablation.

Indexed as

atrial fibrillationcatheter ablationcryoablationneuECGskin sympathetic nerve activity

Identifiers

PMID36531709
PMCPMC9748148

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.