Evidence map›Paper›PMID 36536333›Full record

Trial reportBMC musculoskeletal disorders2022

Collagen and platelet-rich plasma in partial-thickness rotator cuff injuries. Friends or only indifferent neighbours? Randomised controlled trial.

Piotr Godek, Beata Szczepanowska-Wolowiec, Dominik Golicki

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04492748 (Collagen and PRP in Partial Thickness Rotator Cuff Injuries), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04492748 phase4unknown statusnot on this map

Collagen and PRP in Partial Thickness Rotator Cuff Injuries: Friends or Only Indifferent Neighbors: Randomized Controlled Trial

TypeinterventionalSponsorSutherland Medical CenterRan2020 to 2021Enrolled90ConditionsRotator Cuff Tendinosis, Rotator Cuff TearsArmsCollagen and platelet rich plasma (PRP), Collagen, Platelet rich plasma (PRP)
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Piotr GodekSutherland Medical Center, 04-036, Warsaw, Poland. piotrgodek.smc@gmail.com.
Beata Szczepanowska-WolowiecInstitute of Health Sciences, Collegium Medicum, The Jan Kochanowski University, Kielce, Poland.
Dominik GolickiDepartment of Experimental and Clinical Pharmacology, Medical University of Warsaw, Warsaw, Poland.
Jan Kochanowski University · PLMedical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPartial-thickness rotator cuff injuries (PTRCI) are the sum of degenerative, overload, and microtrauma processes. An external supply of collagen and platelet-rich plasma (PRP) could potentially counteract the deterioration of degenerative tendinopathy. This study aimed to compare the effectiveness of collagen with PRP, PRP alone, and collagen alone in the treatment of PTRCI.

methodsNinety patients with PTRCI were randomised and treated with ultrasound-guided injections into the shoulder bursa every consecutive week: Group A - collagen with PRP (n = 30), Group B - collagen alone (n = 30), and Group C - PRP alone (n = 30). Primary outcomes were pain intensity measured in control points on a numeric rating scale (NRS), QuickDash, and EQ-5D-5L questionnaires at the initial assessment (IA) and control assessments after 6 (T1), 12 (T2), and 24 (T3) weeks, respectively.

resultsNo statistical differences were found between groups in primary outcomes, although there was a trend towards improvement in Groups A and C (opposite to Group B) between T2 and T3. The following parameters were also observed: rotator cuff discontinuity (n = 3, one case in each group) and rotator cuff regeneration (n = 22 in Group A, n = 20 in Group B, and n = 23 in Group C).

conclusionsCombined therapy of collagen and PRP in PTRCI presents similar effectiveness to monotherapies with collagen or PRP.

trial registrationThe study was prospectively registered on the NCT Trial Center (identification number: NCT04492748 ) on 30.07.2020.

Indexed as

Platelet-Rich PlasmaRotator Cuff InjuriesArthroscopyCollagenFriendsHumansRotator CuffTreatment OutcomeCollagenCollagenConservative treatmentPlatelet-rich plasmaRotator cuffTendinopathy

Identifiers

PMID36536333
PMCPMC9764482
OpenAlexW4311935921

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.