Evidence map›Paper›PMID 36538062›Full record

ArticleDiabetologia2023

Changes in attitudes to awareness of hypoglycaemia during a hypoglycaemia awareness restoration programme are associated with avoidance of further severe hypoglycaemia episodes within 24 months: the A2A in HypoCOMPaSS study.

Eduardo Sepúlveda, Peter Jacob, Rui Poínhos, Davide Carvalho, Selene G Vicente, Emma L Smith, James A M Shaw, Jane Speight, Pratik Choudhary, Nicole de Zoysa and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Diabetologia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Validating and Establishing a Diagnostic Threshold for the Hypoglycemia Awareness Questionnaire Impaired Awareness Subscale.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2023
    Article
  7. Validation of Igls Criteria for Islet Transplant Functional Status Using Person-Reported Outcome Measures in a Cross-Sectional Study.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Eduardo SepúlvedaDiabetes Research Group, King's College London, London, UK.ORCID 0000-0002-9833-082X
Peter JacobDiabetes Research Group, King's College London, London, UK.
Rui PoínhosFaculty of Nutrition and Food Sciences, Universidade do Porto, Porto, Portugal.ORCID 0000-0002-9177-6423
Davide CarvalhoDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.ORCID 0000-0002-3156-3741
Selene G VicenteCentre for Psychology at Universidade do Porto, Faculty of Psychology and Educational Sciences, Universidade do Porto, Porto, Portugal.ORCID 0000-0003-1840-118X
Emma L SmithDiabetes Research Group, King's College London, London, UK.
James A M ShawTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK. jim.shaw@ncl.ac.uk.ORCID 0000-0002-2893-3211
Jane SpeightSchool of Psychology, Deakin University, Geelong, VIC, Australia.ORCID 0000-0002-1204-6896
Pratik ChoudharyDiabetes Research Group, King's College London, London, UK.ORCID 0000-0001-7635-4735
Nicole de ZoysaDiabetes Research Group, King's College London, London, UK.
Stephanie A AmielDiabetes Research Group, King's College London, London, UK. stephanie.amiel@kcl.ac.uk.ORCID 0000-0003-2686-5531
HypoCOMPaSS Study Group
King's College London · GBUniversidade do Porto · PTDeakin University · AUi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto · PTKing's College Hospital NHS Foundation Trust · GBNewcastle University · GBUniversity of Leicester · GB

Funding

Diabetes UK 07/0003556
6 · The paper itself

Abstract

aims/hypothesisThe aims of this study were to assess cognitions relating to hypoglycaemia in adults with type 1 diabetes and impaired awareness of hypoglycaemia before and after the multimodal HypoCOMPaSS intervention, and to determine cognitive predictors of incomplete response (one or more severe hypoglycaemic episodes over 24 months).

methodsThis analysis included 91 adults with type 1 diabetes and impaired awareness of hypoglycaemia who completed the Attitudes to Awareness of Hypoglycaemia (A2A) questionnaire before, 24 weeks and 24 months after the intervention, which comprised a short psycho-educational programme with optimisation of insulin therapy and glucose monitoring.

resultsThe age and diabetes duration of the participants were 48±12 and 29±12 years, respectively (mean±SD). At baseline, 91% reported one or more severe hypoglycaemic episodes over the preceding 12 months; this decreased to <20% at 24 weeks and after 24 months (p=0.001). The attitudinal barrier 'hyperglycaemia avoidance prioritised' (η CONCLUSIONS/

interpretationParticipation in the HypoCOMPaSS RCT was associated with improvements in hypoglycaemia-associated cognitions, with 'hyperglycaemia avoidance prioritised' most prevalent. Incomplete prevention of subsequent severe hypoglycaemia episodes was associated with persistence of the cognition 'asymptomatic hypoglycaemia normalised'. Understanding and addressing cognitive barriers to hypoglycaemia avoidance is important in individuals prone to severe hypoglycaemia episodes. CLINICAL TRIALS REGISTRATION: www.isrctn.org : ISRCTN52164803 and https://eudract.ema.europa.eu : EudraCT2009-015396-27.

Indexed as

Diabetes Mellitus, Type 1HyperglycemiaHypoglycemiaAdultAttitudeAwarenessBlood GlucoseBlood Glucose Self-MonitoringHumansHypoglycemic AgentsInsulinBlood GlucoseHypoglycemic AgentsInsulinHypoglycaemiaImpaired awareness of hypoglycaemiaType 1 diabetes

Identifiers

PMID36538062
PMCPMC9947080
OpenAlexW4312019403

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.