Evidence mapPaperPMID 36539623Full record

ArticleActa diabetologica2023

Regional divergence and time trends in the prevalence of gestational diabetes mellitus: a national Danish cohort study.

Cathrine M Scheuer, Maria H Andersen, Elisabeth R Mathiesen, Lene Ringholm, Clara L Müller, Jun-Mei Truong, Michelle M Lie-Olesen, Martin Overgaard, H David McIntyre, Dorte M Jensen and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Acta diabetologica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Gestational Diabetes: An Update 60 Years After O'Sullivan and Mahan.The Journal of clinical endocrinology and metabolism · 2024
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Cathrine M ScheuerDepartment of Gynaecology and Obstetrics, Nordsjællands Hospital, Hillerød, Denmark. cathrine.munk.scheuer.01@regionh.dk.ORCID http://orcid.org/0000-0001-6798-7696
Maria H AndersenDepartment of Gynaecology and Obstetrics, Nordsjællands Hospital, Hillerød, Denmark.
Elisabeth R MathiesenDepartment of Endocrinology and Metabolism, Center for Pregnant Women with Diabetes, Copenhagen, Denmark.
Lene RingholmDepartment of Endocrinology and Metabolism, Center for Pregnant Women with Diabetes, Copenhagen, Denmark.
Clara L MüllerDepartment of Gynaecology and Obstetrics, Nordsjællands Hospital, Hillerød, Denmark.
Jun-Mei TruongDepartment of Gynaecology and Obstetrics, Nordsjællands Hospital, Hillerød, Denmark.
Michelle M Lie-OlesenDepartment of Gynaecology and Obstetrics, Nordsjællands Hospital, Hillerød, Denmark.
Martin OvergaardDepartment of Clinical Biochemistry, Odense University Hospital, Odense, Denmark.
H David McIntyreMater Clinical Unit, Faculty of Medicine, The University of Queensland, Brisbane, Australia.
Dorte M JensenSteno Diabetes Center Odense, Odense University Hospital, Odense, Denmark.
Peter DammDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Tine D ClausenDepartment of Gynaecology and Obstetrics, Nordsjællands Hospital, Hillerød, Denmark.
Nordsjællands Hospital · DKUniversity of Copenhagen · DKSteno Diabetes Centers · DKThe University of Queensland · AUTuen Mun Hospital · CNUniversity of Southern Denmark · DK

Funding

Danish Diabetes Academy NNF17SA0031406Nordsjællands Hospital E-20225-17-04Region Hovedstaden R154-A6286
6 · The paper itself

Abstract

aimsTo evaluate the prevalence and time trends of gestational diabetes mellitus (GDM) across the five regions of Denmark with uniform national guidelines for screening and diagnosing GDM.

methodsThis register-based national cohort study included 287,684 births from 2013 to 2017. Trends in GDM prevalence over time and differences between the five regions were evaluated. Crude and adjusted odd ratios (ORs) for GDM were calculated including potential confounding clinical risk factors as age, BMI, educational level, marital status, parity, country of origin and assisted reproduction.

resultsFrom 2013 to 2017, GDM prevalence in Denmark increased by 7% per year (OR 1.07, 95% CI 1.06-1.09, P < 0.001). GDM prevalence varied considerably between regions and ranged from 3.0 to 5.9% in 2017, corresponding to a maximal regional difference of 97%. In crude analyses, the risk of GDM in 2017 was significantly different in four of five regions compared to the remaining regions (OR ranging from 0.60 to 1.55), and these differences persisted after adjusting for confounding clinical risk factors (adjusted OR: 0.59-1.45).

conclusionThe prevalence of GDM increased over time in all Danish regions with substantial regional divergence. Up to a 97%, difference in GDM prevalence was observed between Danish regions, which was not explained by available clinical risk factors. This occurred despite national guidelines and raises the question of whether regional variations in screening efficacy, diagnostic procedures or inequality in clinical health care access may explain the observed differences.

Indexed as

Diabetes, GestationalCohort StudiesDenmarkFemaleHumansPregnancyPrevalenceRisk FactorsDenmarkGestational diabetes mellitusPregnancyPrevalenceRegistries

Identifiers

PMID36539623
PMCPMC9931790
OpenAlexW4312067614

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.