Evidence map›Paper›PMID 36545352›Full record

ArticleFrontiers in human neuroscience2022

Maternal blood inflammatory marker levels increased in fetuses with ventriculomegaly.

Qiang Li, Xin-Wei Ju, Jing Xu, Jiuhong Jiang, Chang Lu, Xing-Da Ju

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Article in Frontiers in human neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qiang LiSchool of Psychology, Northeast Normal University, Changchun, China.
Xin-Wei JuDepartment of Radiology, The First Hospital of Jilin University, Changchun, China.
Jing XuSchool of Life Sciences, Northeast Normal University, Changchun, China.
Jiuhong JiangSchool of Information Science and Technology, Northeast Normal University, Changchun, China.
Chang LuSchool of Psychology, Northeast Normal University, Changchun, China.
Xing-Da JuSchool of Psychology, Northeast Normal University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fetal ventriculomegaly (VM) is one of the most common abnormalities of the central nervous system (CNS), which can be significantly identified by brain anomalies prenatally by magnetic resonance imaging (MRI). Aberrant white blood cells (WBCs) levels indicate that the maternal is suffering from the infection. Previous studies have confirmed that prenatal infection can affect fetal brain structure, but there is no research revealed the association between maternal blood parameters with fetal VM until now. Methods: We measured the width of the lateral ventricle of 142 fetuses, which were divided into the fetal VM group ( Result: High levels of maternal WBC and neutrophil (NE#) levels were observed in fetuses with VM ( Conclusion: The current study emphasizes the importance of maternal infection for fetal brain growth, which could provide important information for prenatal diagnosis of CNS anomalies. Future research needs longitudinal analysis and exploration of the influence of maternal blood inflammatory marker levels on fetal brain development.

Indexed as

biomarkers brain alterationsfetal ventriculomegalyinflammatory markersneurodevelopmentprenatal infection

Identifiers

PMID36545352
PMCPMC9760835

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.