Evidence map›Paper›PMID 36547340›Full record

ReviewGels (Basel, Switzerland)2022

Recent Advances in Hydrogels for the Diagnosis and Treatment of Dry Eye Disease.

Qiaoqiao Li, Yifeng Cao, Ping Wang

Open access · goldAbstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Qiaoqiao LiCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China.
Yifeng CaoInstitute of Electronic Chemicals, Institute of Zhejiang University-Quzhou, Quzhou 324000, China.ORCID 0000-0002-1352-5709
Ping WangCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China.
Zhejiang University of Technology · CNQuzhou University · CN

Funding

Research Funds of Institute of Zhejiang University-Quzhou IZQ2022RCZX004the Science and Technology Planning Project of Jinhua 2020-1-025the Science Technology Department of Zhejiang Province 2022C02013the Science Technology Department of Zhejiang Province 2022C03050
6 · The paper itself

Abstract

Dry eye disease (DED) is the most common clinical ocular surface disease. Given its multifactorial etiology, no consensus has been reached on the diagnosis criteria for dry eye disease. Topical drug administration remains the mainstay of treatment but is limited to the rapid clearance from the eye surface. To address these problems, hydrogel-based materials were designed to detect biomarkers or act as drug delivery systems by taking advantage of their good biocompatibility, excellent physical and mechanical properties, and long-term implant stability. Biosensors prepared using biocompatible hydrogels can be sensitive in diagnosing DED, and the designed hydrogels can also improve the drug bioavailability and retention time for more effective and long-term treatment. This review summarizes recent advances in the use of hydrogels for diagnosing and treating dry eye, aiming to provide a novel reference for the eventual clinical translation of hydrogels in the context of dry eye disease.

Indexed as

biosensorcontrolled releasediagnosis and treatmentdry eye diseasehydrogels

Identifiers

PMID36547340
PMCPMC9778550
OpenAlexW4312128003

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.