Evidence map›Paper›PMID 36552463›Full record

ArticleAnimals : an open access journal from MDPI2022

Effects of Dietary Supplementation of

Elena Colombino, Ilaria Biasato, Alberta Michetti, Maria Gabriella Rubino, Irene Franciosa, Marzia Giribaldi, Sara Antoniazzi, Stefania Bergagna, Giulia Paliasso, Ilario Ferrocino and 3 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Influence ofOpen veterinary journal · 2026
    Article
  3. Article
  4. Review
  5. Dietary probiotic supplementation withAnimal biotechnology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Elena ColombinoDepartment of Veterinary Sciences, University of Turin, 10095 Grugliasco, TO, Italy.ORCID 0000-0002-6371-2000
Ilaria BiasatoDepartment of Agricultural, Forestry and Food Sciences, University of Turin, 10095 Grugliasco, TO, Italy.ORCID 0000-0002-8855-4248
Alberta MichettiDepartment of Veterinary Sciences, University of Turin, 10095 Grugliasco, TO, Italy.
Maria Gabriella RubinoDepartment of Veterinary Sciences, University of Turin, 10095 Grugliasco, TO, Italy.
Irene FranciosaDepartment of Agricultural, Forestry and Food Sciences, University of Turin, 10095 Grugliasco, TO, Italy.ORCID 0000-0001-9540-3387
Marzia GiribaldiInstitute of Sciences of Food Production, CNR, 10095 Grugliasco, TO, Italy.ORCID 0000-0003-3507-7684
Sara AntoniazziInstitute of Sciences of Food Production, CNR, 10095 Grugliasco, TO, Italy.
Stefania BergagnaIstituto Zooprofilattico Sperimentale del Piemonte, 10154 Liguria e Valle d'Aosta, TO, Italy.ORCID 0000-0001-5390-4108
Giulia PaliassoIstituto Zooprofilattico Sperimentale del Piemonte, 10154 Liguria e Valle d'Aosta, TO, Italy.ORCID 0000-0003-2332-9784
Ilario FerrocinoDepartment of Agricultural, Forestry and Food Sciences, University of Turin, 10095 Grugliasco, TO, Italy.ORCID 0000-0002-1657-0054
Laura CavallarinInstitute of Sciences of Food Production, CNR, 10095 Grugliasco, TO, Italy.ORCID 0000-0001-7006-1683
Laura GascoDepartment of Agricultural, Forestry and Food Sciences, University of Turin, 10095 Grugliasco, TO, Italy.ORCID 0000-0002-1829-7936
Maria Teresa CapucchioDepartment of Veterinary Sciences, University of Turin, 10095 Grugliasco, TO, Italy.ORCID 0000-0002-1068-0551
University of Turin · ITInstitute of Sciences of Food Production · ITIstituto Zooprofilattico Sperimentale del Piemonte Liguria e Valle d'Aosta · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the effects of Lactobacillus acidophilus D2/CSL (L-1 × 109 cfu/kg feed/day) on biochemical parameters, faecal score (FS), cecal pH, gut morphometry, microbiota and cecal short-chain fatty acid (SCFAs) in rabbits. Three zootechnical trials were performed and in each trial 30 rabbits were allotted to two groups; a probiotic group (L) and a control group (C). At slaughter (day 45), samples of blood, duodenum, jejunum, ileum, liver and spleen were collected and submitted to histomorphometric analyses. Blood biochemical analyses, cecal microbiota and SCFAs determination were also performed. In trial 1 and 3, L. acidophilus D2/CSL did not affect productive parameters (p > 0.05). However, L group of trial 1 showed a lower morbidity and mortality compared to the control. In trial 2, C group showed a higher daily feed intake (p = 0.018) and a positive statistical tendency for live weight and average daily gain (p = 0.068). On the contrary, albumin was higher and ALFA-1 globulin was lower in the C group compared to L (p < 0.05). In all the trials, FS, cecal pH, histomorphometry, microbiota and SCFAs were unaffected. In conclusion, L. acidophilus D2/CSL did not impair growth performances, gut and rabbit’s health, reducing morbidity and mortality.

Indexed as

animal healthgut healthLactobacillus acidophilusprobioticrabbit

Identifiers

PMID36552463
PMCPMC9774759
OpenAlexW4311612557

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.