ReviewCells2022
Effects of Heat Stress on Bovine Oocytes and Early Embryonic Development-An Update.
Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 40 citations in OpenAlex.
- Nutritional Modulation of Epigenetic Responses to Heat Stress in Farm Animals: Evidence, Limitations and Perspectives.Animals : an open access journal from MDPI · 2026Review
- Delayed ovulation in cattle: Physiological mechanisms, diagnostic approaches, and reproductive management strategies.Veterinary world · 2026Article
- The Effect of Heat Treatment on the Gene Expression and Cryosurvival of In Vitro-Produced Bovine Embryos.Animals : an open access journal from MDPI · 2026Article
- Advances in bovine oocyte in vitro maturation: mechanisms and strategies.Veterinary research communications · 2026Review
- Ovarian Function, Hormonal, Metabolic, Oxidative Stress, and Gene Expression Biomarker Responses of Holstein Heifers Under Heat Stress Conditions to a Reduced Dose of Nanofabricated GnRH Analog Within the Ovsynch Protocol.Animals : an open access journal from MDPI · 2026Article
- Establishment and characterization of Hanwoo cumulus cell line for heat stress studies.Animal bioscience · 2026Article
- In vivo use of melatonin improves oocyte developmental competence and blastocyst development rate in indigenous donor cow during summer.Tropical animal health and production · 2026Article
- Consequences of Heat Stress on Physiology, Microbiome Dynamics, and Multi-Omics in Dairy Cows: More than Meets the Eye.Biology · 2026Review
- Oocyte aging in focus: Environmental and endogenous stressors driving reproductive potential decline.GeroScience · 2026Review
- Review
- Impact of lauric acid supplementation on bovine oocyte maturation, IVF embryo development, and stress protection during IVM.Animal reproduction · 2026Article
- Molecular and developmental consequences of heat stress on the bovine oocyte and embryo competence.Animal reproduction · 2026Article
- Influence of heat stress and nighttime recovery on ovarian follicle population, oocyte yield, and in vitro embryo production in Holstein heifers.Archives animal breeding · 2026Article
- A new type of biomarker for heat stress: insights from immunology.Frontiers in immunology · 2026Review
- Heat Shock Differentially Compromises Embryonic Development and Gene Expression in a Mouse Embryoid Body Model System.Animals : an open access journal from MDPI · 2025Article
- Effects of Heat Stress on Estrus Expression and Pregnancy in Dairy Cows.Animals : an open access journal from MDPI · 2025Article
- Estradiol Alleviates Elevated Temperature-Induced Damage in Yak Oviductal Epithelial Cells by Maintaining Endoplasmic Reticulum Calcium Homeostasis.Animals : an open access journal from MDPI · 2025Article
- METTL7A improves bovine IVF embryo competence by attenuating oxidative stress†.Biology of reproduction · 2025Article
- Metabolomics of follicular fluid reveals the impact of heat stress on oocyte pick-up and in vitro embryo production efficiency in dairy cows.Journal of animal science · 2025Article
- Heat stress affects dairy cow performance via oxidative stress, hypothalamic-pituitary-adrenal axis, gut microbiota, and multi-dimensional mitigation.Frontiers in veterinary science · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heat stress is a major threat to cattle reproduction today. It has been shown that the effect of high temperature not only has a negative effect on the hormonal balance, but also directly affects the quality of oocytes, disrupting the function of mitochondria, fragmenting their DNA and changing their maternal transcription. Studies suggest that the induction of HSP70 may reduce the apoptosis of granular layer cells caused by heat stress. It has been shown that the changes at the transcriptome level caused by heat stress are consistent with 46.4% of blastocyst development disorders. Cows from calves exposed to thermal stress in utero have a lower milk yield in their lifetime, exhibit immunological disorders, have a lower birth weight and display a shorter lifespan related to the expedited aging. In order to protect cow reproduction, the effects of heat stress at the intracellular and molecular levels should be tracked step by step, and the impacts of the dysregulation of thermal homeostasis (i.e., hyperthermy) should be taken into account.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.