Evidence map›Paper›PMID 36553812›Full record

ArticleFoods (Basel, Switzerland)2022

Phytochemical Profiling and Untargeted Metabolite Fingerprinting of the MEDWHEALTH Wheat, Barley and Lentil Wholemeal Flours.

Giuseppe Romano, Laura Del Coco, Francesco Milano, Miriana Durante, Samuela Palombieri, Francesco Sestili, Andrea Visioni, Abderrazek Jilal, Francesco Paolo Fanizzi, Barbara Laddomada

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Effects of Traditional MoroccanFoods (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Characterization ofFrontiers in plant science · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giuseppe RomanoInstitute of Sciences of Food Production (ISPA), National Research Council (CNR), via Monteroni, 73100 Lecce, Italy.
Laura Del CocoDepartment of Biological and Environmental Sciences and Technologies (Di.S.Te.B.A.), University of Salento, via Monteroni, 73100 Lecce, Italy.ORCID 0000-0002-4805-7538
Francesco MilanoInstitute of Sciences of Food Production (ISPA), National Research Council (CNR), via Monteroni, 73100 Lecce, Italy.ORCID 0000-0001-5453-2051
Miriana DuranteInstitute of Sciences of Food Production (ISPA), National Research Council (CNR), via Monteroni, 73100 Lecce, Italy.ORCID 0000-0002-1779-6426
Samuela PalombieriDepartment of Agriculture and Forest Sciences (DAFNE), University of Tuscia, 01100 Viterbo, Italy.ORCID 0000-0003-3243-3428
Francesco SestiliDepartment of Agriculture and Forest Sciences (DAFNE), University of Tuscia, 01100 Viterbo, Italy.ORCID 0000-0002-9653-8002
Andrea VisioniInternational Center for Agricultural Research in the Dry Areas (ICARDA), Biodiversity and Crop Improvement Program, Rabat P.O. Box 6299, Morocco.ORCID 0000-0002-0586-4532
Abderrazek JilalNational Institute for Agricultural Research Morocco (INRAM), Rabat P.O. Box 415, Morocco.ORCID 0000-0002-9147-9074
Francesco Paolo FanizziDepartment of Biological and Environmental Sciences and Technologies (Di.S.Te.B.A.), University of Salento, via Monteroni, 73100 Lecce, Italy.ORCID 0000-0003-3073-5772
Barbara LaddomadaInstitute of Sciences of Food Production (ISPA), National Research Council (CNR), via Monteroni, 73100 Lecce, Italy.ORCID 0000-0002-7492-6039

Funding

PRIMA Section 1 2020 Agrofood Value ChainIA Topic: 1.3.1-2020 (IA), MEDWHEALTH 2034
6 · The paper itself

Abstract

An important research target is improving the health benefits of traditional Mediterranean, durum wheat-based foods using innovative raw materials. In this study, we characterised wholemeal flours obtained from a traditional durum wheat cv. Svevo, two innovative durum wheat varieties (Svevo-High Amylose and Faridur), the naked barley cv. Chifaa and the elite lentil line 6002/ILWL118/1-1, evaluating them for targeted phytochemicals, untargeted metabolomics fingerprints and antioxidant capacity. To this aim, individual phenolic acids, flavonoids, tocochromanols and carotenoids were identified and quantified through HPLC-DAD, and the antioxidant capacities of both the extracts and whole meals were detected by ABTS assays. An untargeted metabolomics fingerprinting of the samples was conducted through NMR spectroscopy. Results showed that the innovative materials improved phytochemical profiles and antioxidant capacity compared to Svevo. In particular, Svevo-HA and Faridur had higher contents of ferulic and sinapic acids, β-tocotrienol and lutein. Moreover, Chifaa is a rich source of phenolic acids, β-tocopherols, lutein and zeaxanthin whereas lentil of flavonoids (i.e., catechin and procyanidin B2). The NMR profiles of Svevo-HA and Faridur showed a significant reduction of sugar content, malate and tryptophan compared to that of Svevo. Finally, substantial differences characterised the lentil profiles, especially for citrate, trigonelline and phenolic resonances of secondary metabolites, such as catechin-like compounds. Overall, these results support the potential of the above innovative materials to renew the health value of traditional Mediterranean durum wheat-based products.

Indexed as

antioxidant activitydurum wheat-based productsisoprenoidsmetabolomicsNMRpolyphenolsresistant starch

Identifiers

PMID36553812
PMCPMC9777840

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.