Evidence map›Paper›PMID 36555486›Full record

ArticleInternational journal of molecular sciences2022

Application of Long-Read Nanopore Sequencing to the Search for Mutations in Hypertrophic Cardiomyopathy.

Ramil R Salakhov, Maria V Golubenko, Nail R Valiakhmetov, Elena N Pavlyukova, Aleksei A Zarubin, Nadezhda P Babushkina, Aksana N Kucher, Aleksei A Sleptcov, Maria S Nazarenko

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Frontiers in genetics · 2026
    Article
  2. Article
  3. Special Issue: "Genes and Human Diseases".International journal of molecular sciences · 2024
    Article
  4. Article
  5. Discovering a novel glycosyltransferase geneFrontiers in microbiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ramil R SalakhovResearch Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences, 634050 Tomsk, Russia.ORCID 0000-0002-9789-9555
Maria V GolubenkoResearch Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences, 634050 Tomsk, Russia.
Nail R ValiakhmetovResearch Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences, 634050 Tomsk, Russia.
Elena N PavlyukovaCardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, 634012 Tomsk, Russia.
Aleksei A ZarubinResearch Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences, 634050 Tomsk, Russia.
Nadezhda P BabushkinaResearch Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences, 634050 Tomsk, Russia.
Aksana N KucherResearch Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences, 634050 Tomsk, Russia.
Aleksei A SleptcovResearch Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences, 634050 Tomsk, Russia.ORCID 0000-0003-3226-1750
Maria S NazarenkoResearch Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences, 634050 Tomsk, Russia.
Russian Academy of Sciences · RU

Funding

Russian Science Foundation 22-24-01164
6 · The paper itself

Abstract

Increasing evidence suggests that both coding and non-coding regions of sarcomeric protein genes can contribute to hypertrophic cardiomyopathy (HCM). Here, we introduce an experimental workflow (tested on four patients) for complete sequencing of the most common HCM genes (

Indexed as

Cardiomyopathy, HypertrophicNanopore SequencingCarrier ProteinsHumansMutationTroponin TCarrier ProteinsTroponin Thypertrophic cardiomyopathylong-read sequencingOxford Nanoporesarcomeric protein genes

Identifiers

PMID36555486
PMCPMC9779642
OpenAlexW4312194584

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.