Evidence map›Paper›PMID 36555749›Full record

ReviewInternational journal of molecular sciences2022

Advances in Imaging of Inflammation, Fibrosis, and Cancer in the Gastrointestinal Tract.

Kylene M Harold, William M MacCuaig, Jennifer Holter-Charkabarty, Kirsten Williams, Kaitlyn Hill, Alex X Arreola, Malika Sekhri, Steven Carter, Jorge Gomez-Gutierrez, George Salem and 2 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Assessment of Breast Tumors Using Multispectral Optoacoustic Tomography in a Surgical Setting.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Trial
  2. Radiology. Imaging cancer · 2025
    Trial
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Radiology of fibrosis part II: abdominal organs.Journal of translational medicine · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. How to Evaluate Fibrosis in IBD?Diagnostics (Basel, Switzerland) · 2023
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kylene M HaroldDepartment of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.ORCID 0000-0002-8421-6268
William M MacCuaigDepartment of Bioengineering, University of Oklahoma, Norman, OK 73019, USA.
Jennifer Holter-CharkabartyDepartment of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Kirsten WilliamsSchool of Medicine, Emory University, Atlanta, GA 30322, USA.
Kaitlyn HillDepartment of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Alex X ArreolaDepartment of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Malika SekhriDepartment of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Steven CarterDepartment of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Jorge Gomez-GutierrezDepartment of Child Health, School of Medicine, University of Missouri, Columbia, MO 65211, USA.ORCID 0000-0003-3610-260X
George SalemDepartment of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Girish MishraWake Forest Baptist Health, Winston-Salem, NC 27157, USA.
Lacey R McNallyDepartment of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

Funding

Non-Invasive Detection of Tumor Extracellular pH using Multispectral Optoacoustic TomographyR01CA205941 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MCNALLY, LACEY R · 2016 to 2021
$1.7M
Tumor-Specific Nanocontrast Agents for Improved Detection of Pancreatic CancerF31CA261044 · NCI · UNIVERSITY OF OKLAHOMA · PI MACCUAIG, WILLIAM · 2022 to 2023
$79k
NCI NIH HHS F31CA261044, R01CA205941, R01CA212350NCI NIH HHS R01 CA205941
6 · The paper itself

Abstract

Gastrointestinal disease is prevalent and broad, manifesting itself in a variety of ways, including inflammation, fibrosis, infection, and cancer. However, historically, diagnostic technologies have exhibited limitations, especially with regard to diagnostic uncertainty. Despite development of newly emerging technologies such as optoacoustic imaging, many recent advancements have focused on improving upon pre-existing modalities such as ultrasound, computed tomography, magnetic resonance imaging, and endoscopy. These advancements include utilization of machine learning models, biomarkers, new technological applications such as diffusion weighted imaging, and new techniques such as transrectal ultrasound. This review discusses assessment of disease processes using imaging strategies for the detection and monitoring of inflammation, fibrosis, and cancer in the context of gastrointestinal disease. Specifically, we include ulcerative colitis, Crohn's disease, diverticulitis, celiac disease, graft vs. host disease, intestinal fibrosis, colorectal stricture, gastric cancer, and colorectal cancer. We address some of the most recent and promising advancements for improvement of gastrointestinal imaging, including unique discussions of such advancements with regard to imaging of fibrosis and differentiation between similar disease processes.

Indexed as

Gastrointestinal DiseasesNeoplasmsEndoscopy, GastrointestinalFibrosisHumansInflammationMagnetic Resonance ImagingTomography, X-Ray Computedcancerfibrosisgastrointestinal tractimaginginflammation

Identifiers

PMID36555749
PMCPMC9781634

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.