Evidence mapPaperPMID 36556255Full record

ReviewJournal of personalized medicine2022

Personalized Medicine and Obstructive Sleep Apnea.

Sy Duong-Quy, Hoang Nguyen-Huu, Dinh Hoang-Chau-Bao, Si Tran-Duc, Lien Nguyen-Thi-Hong, Thai Nguyen-Duy, Tram Tang-Thi-Thao, Chandat Phan, Khue Bui-Diem, Quan Vu-Tran-Thien and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Neuro-Ophthalmological Disorders Associated with Obstructive Sleep Apnoea.International journal of molecular sciences · 2025
    Review
  6. Exploring Exercise Interventions for Obstructive Sleep Apnea: A Scoping Review.Journal of functional morphology and kinesiology · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Observational
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Sy Duong-QuySleep Lab Centre, Lam Dong Medical College, Dalat City 0263, Vietnam.ORCID 0000-0002-5926-9544
Hoang Nguyen-HuuMedical Education Center, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 0028, Vietnam.
Dinh Hoang-Chau-BaoSleep Lab Unit, Outpatient Department, Pham Ngoc Thach Medical University, Ho Chi Minh City 0028, Vietnam.
Si Tran-DucSleep Lab Unit, Outpatient Department, Pham Ngoc Thach Medical University, Ho Chi Minh City 0028, Vietnam.
Lien Nguyen-Thi-HongImmuno-Allergology Department, Hai Phong Medical University, Hai Phong City 0225, Vietnam.ORCID 0000-0003-4625-456X
Thai Nguyen-DuyNational Institute for Control of Vaccines and Biologicals, Ministry of Health, Hanoi City 0024, Vietnam.
Tram Tang-Thi-ThaoSleep Lab Centre, Lam Dong Medical College, Dalat City 0263, Vietnam.
Chandat PhanImmuno-Allergology Division, Hershey Medical Center, Penn State Medical College, Hershey, PA 15747, USA.
Khue Bui-DiemDepartment of Physiology-Pathophysiology-Immunology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 0028, Vietnam.ORCID 0000-0003-0918-8049
Quan Vu-Tran-ThienDepartment of Respiratory Functional Exploration, University Medical Center, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 0028, Vietnam.
Thu Nguyen-Ngoc-PhuongSleep Lab Unit, Outpatient Department, Pham Ngoc Thach Medical University, Ho Chi Minh City 0028, Vietnam.
Vinh Nguyen-NhuDepartment of Respiratory Functional Exploration, University Medical Center, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 0028, Vietnam.ORCID 0000-0002-8358-902X
Huong Le-Thi-MinhPediatric Centre, Vinmec Times City International Hospital, Hanoi City 0024, Vietnam.
Timothy CraigSleep Lab Centre, Lam Dong Medical College, Dalat City 0263, Vietnam.ORCID 0000-0002-7774-4855
Pham Ngoc Thach University of Medicine · VNUniversity of Medicine and Pharmacy at Ho Chi Minh City · VNPenn State Milton S. Hershey Medical Center · USHai phong University Of Medicine and Pharmacy · VNMinistry of Health · VNVinmec International Hospital · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) is a common disease that is often under-diagnosed and under-treated in all ages. This is due to differences in morphology, diversity in clinical phenotypes, and differences in diagnosis and treatment of OSA in children and adults, even among individuals of the same age. Therefore, a personalized medicine approach to diagnosis and treatment of OSA is necessary for physicians in clinical practice. In children and adults without serious underlying medical conditions, polysomnography at sleep labs may be an inappropriate and inconvenient testing modality compared to home sleep apnea testing. In addition, the apnea-hypopnea index should not be considered as a single parameter for making treatment decisions. Thus, the treatment of OSA should be personalized and based on individual tolerance to sleep-quality-related parameters measured by the microarousal index, harmful effects of OSA on the cardiovascular system related to severe hypoxia, and patients' comorbidities. The current treatment options for OSA include lifestyle modification, continuous positive airway pressure (CPAP) therapy, oral appliance, surgery, and other alternative treatments. CPAP therapy has been recommended as a cornerstone treatment for moderate-to-severe OSA in adults. However, not all patients can afford or tolerate CPAP therapy. This narrative review seeks to describe the current concepts and relevant approaches towards personalized management of patients with OSA, according to pathophysiology, cluster analysis of clinical characteristics, adequate combined therapy, and the consideration of patients' expectations.

Indexed as

apnea–hypopnea indexCPAPhome sleep apnea testingOSApersonalized managementpolysomnography

Identifiers

PMID36556255
PMCPMC9781564
OpenAlexW4311961341

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.