Evidence map›Paper›PMID 36556936›Full record

ArticleMedicina (Kaunas, Lithuania)2022

Distinct Expression Patterns of Genes Coding for Biological Response Modifiers Involved in Inflammatory Responses and Development of Fibrosis in Chronic Hepatitis C: Upregulation of SMAD-6 and MMP-8 and Downregulation of CAV-1, CTGF, CEBPB, PLG, TIMP-3, MMP-1, ITGA-1, ITGA-2 and LOX.

Leona Radmanić, Petra Korać, Lana Gorenec, Petra Šimičić, Kristian Bodulić, Adriana Vince, Snježana Židovec Lepej

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Leona RadmanićDepartment of Immunological and Molecular Diagnostics, University Hospital for Infectious Diseases, "Dr. Fran Mihaljević", HR-10000 Zagreb, Croatia.ORCID 0000-0001-9362-7213
Petra KoraćDivision of Molecular Biology, Department of Biology, Faculty of Science, University of Zagreb, HR-10000 Zagreb, Croatia.ORCID 0000-0003-4783-2114
Lana GorenecDepartment of Immunological and Molecular Diagnostics, University Hospital for Infectious Diseases, "Dr. Fran Mihaljević", HR-10000 Zagreb, Croatia.
Petra ŠimičićDepartment of Immunological and Molecular Diagnostics, University Hospital for Infectious Diseases, "Dr. Fran Mihaljević", HR-10000 Zagreb, Croatia.ORCID 0000-0002-0776-3671
Kristian BodulićResearch Department, University Hospital for Infectious Diseases, "Dr. Fran Mihaljević", HR-10000 Zagreb, Croatia.ORCID 0000-0002-1212-3302
Adriana VinceDepartment of Viral Hepatitis, University Hospital for Infectious Diseases, "Dr. Fran Mihaljević", HR-10000 Zagreb, Croatia.
Snježana Židovec LepejDepartment of Immunological and Molecular Diagnostics, University Hospital for Infectious Diseases, "Dr. Fran Mihaljević", HR-10000 Zagreb, Croatia.ORCID 0000-0001-9852-5806
University Hospital for Infectious Diseases "Dr Fran Mihaljevic" · HRUniversity of Zagreb · HR

Funding

European Regional Development Fund. Strengthening the capacity of CerVirVac for research in virus immunology and vaccinology", KK.01.1.1.01.0006
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hepatitis C, ChronicCCAAT-Enhancer-Binding Protein-betaDown-RegulationEpithelial-Mesenchymal TransitionFibrosisHumansImmunologic FactorsMatrix Metalloproteinase 1Matrix Metalloproteinase 8Tissue Inhibitor of Metalloproteinase-3Transcription FactorsTransforming Growth Factor betaUp-RegulationCCAAT-Enhancer-Binding Protein-betaCEBPB protein, humanImmunologic FactorsMatrix Metalloproteinase 1Matrix Metalloproteinase 8Tissue Inhibitor of Metalloproteinase-3Transcription FactorsTransforming Growth Factor betaCAV-1fibrosisgene expressionhepatitis C infectionSMAD-6

Identifiers

PMID36556936
PMCPMC9785468
OpenAlexW4310213207

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.