Evidence map›Paper›PMID 36557841›Full record

ReviewMolecules (Basel, Switzerland)2022

Nanodelivery of Dietary Polyphenols for Therapeutic Applications.

Mithun Rudrapal, Ashwini K Mishra, Laxmi Rani, Khomendra K Sarwa, James H Zothantluanga, Johra Khan, Mehnaz Kamal, Santwana Palai, Atul R Bendale, Swati G Talele and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Preparation of silibinin- dendrimer-stabilized Au nanoparticles for decreasing vancomycin resistance in S. aureus clinical isolates.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
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  10. Therapeutic Potential of Plant Phenolic Acids Combating Cancer Drug Resistance.Recent advances in food, nutrition & agriculture · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Mithun RudrapalDepartment of Pharmaceutical Chemistry, Rasiklal M. Dhariwal Institute of Pharmaceutical Education and Research, Pune 411019, India.ORCID 0000-0002-8172-6633
Ashwini K MishraDepartment of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India.
Laxmi RaniDepartment of Pharmacy, School of Medical and Allied Sciences, GD Goenka University, Gurugram 122103, India.ORCID 0000-0003-1341-6876
Khomendra K SarwaDepartment of Pharmacy, Government Girls Polytechnic, Raipur 492001, India.
James H ZothantluangaDepartment of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh 786004, India.
Johra KhanDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al-Majmaah 11952, Saudi Arabia.ORCID 0000-0002-0044-4758
Mehnaz KamalDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.ORCID 0000-0002-3585-0828
Santwana PalaiDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry, Orissa University of Agriculture and Technology (OUAT), Bhubaneswar 751003, India.ORCID 0000-0002-6461-9369
Atul R BendaleSandip Institute of Pharmaceutical Sciences, Nashik 422213, India.ORCID 0000-0002-3219-0377
Swati G TaleleSandip Institute of Pharmaceutical Sciences, Nashik 422213, India.
Vasim T PathanSandip Institute of Pharmaceutical Sciences, Nashik 422213, India.
Laxmikant B BorseSandip Institute of Pharmaceutical Sciences, Nashik 422213, India.ORCID 0000-0002-0857-1604
Vishnu S NeharkarDepartment of Pharmacology, Rasiklal M. Dhariwal Institute of Pharmaceutical Education and Research, Pune 411019, India.
Pravat K SahooDepartment of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India.
Sandip Foundation · INDelhi Pharmaceutical Science and Research University · INDibrugarh University · INGD Goenka University · INMajmaah University · SAOdisha University of Agriculture and Technology · INPrince Sattam Bin Abdulaziz University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advancement in nanotechnology has unleashed the therapeutic potentials of dietary polyphenols by enhancing bioavailability, improving biological half-life, and allowing site-specific drug delivery. In this review, through citation of relevant literature reports, we discuss the application of nano-pharmaceutical formulations, such as solid lipid nanoparticles, nano-emulsions, nano-crystals, nano-polymersomes, liposomes, ethosomes, phytosomes, and invasomes for dietary polyphenols. Following this, we highlight important studies concerning different combinations of nano formulations with dietary polyphenols (also known as nanophytopolyphenols). We also provide nano-formulation paradigms for enhancing the physicochemical properties of dietary polyphenols. Finally, we highlight the latest patents that were granted on nano-formulations of dietary polyphenols. Based on our review, we observe that nanosized delivery of herbal constituents, spices, and dietary supplements have the ability to improve biological processes and address issues connected with herbal treatments.

Indexed as

Drug Delivery SystemsNanoparticlesBiological AvailabilityDietary SupplementsEmulsionsPolyphenolsEmulsionsPolyphenolsdietary polyphenolsnanodeliverynanoformulationnanophytomedicinenanotechnology

Identifiers

PMID36557841
PMCPMC9784807
OpenAlexW4311960148

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.