Evidence map›Paper›PMID 36557962›Full record

ArticleMolecules (Basel, Switzerland)2022

Privileged Scaffold Decoration for the Identification of the First Trisubstituted Triazine with Anti-SARS-CoV-2 Activity.

Silvia Cesarini, Ilaria Vicenti, Federica Poggialini, Massimiliano Secchi, Federica Giammarino, Ilenia Varasi, Camilla Lodola, Maurizio Zazzi, Elena Dreassi, Giovanni Maga and 2 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Discovery of Novel Spike Inhibitors against SARS-CoV-2 Infection.International journal of molecular sciences · 2024
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Silvia CesariniDepartment of Biological and Ecological Sciences, University of Viterbo, Via S.C. De Lellis s.n.c., 01100 Viterbo, Italy.
Ilaria VicentiDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-4306-2960
Federica PoggialiniDepartment of Biotechnology, Chemistry, and Pharmacy (DBCF), University of Siena, 53100 Siena, Italy.
Massimiliano SecchiInstitute of Molecular Genetics, IGM CNR "Luigi Luca Cavalli-Sforza", Via Abbiategrasso 207, 27100 Pavia, Italy.
Federica GiammarinoDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0001-6775-3574
Ilenia VarasiDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Camilla LodolaInstitute of Molecular Genetics, IGM CNR "Luigi Luca Cavalli-Sforza", Via Abbiategrasso 207, 27100 Pavia, Italy.
Maurizio ZazziDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-0344-6281
Elena DreassiDepartment of Biotechnology, Chemistry, and Pharmacy (DBCF), University of Siena, 53100 Siena, Italy.ORCID 0000-0001-8987-940X
Giovanni MagaInstitute of Molecular Genetics, IGM CNR "Luigi Luca Cavalli-Sforza", Via Abbiategrasso 207, 27100 Pavia, Italy.ORCID 0000-0001-8092-1552
Lorenzo BottaDepartment of Biological and Ecological Sciences, University of Viterbo, Via S.C. De Lellis s.n.c., 01100 Viterbo, Italy.ORCID 0000-0002-0856-2986
Raffaele SaladinoDepartment of Biological and Ecological Sciences, University of Viterbo, Via S.C. De Lellis s.n.c., 01100 Viterbo, Italy.ORCID 0000-0002-4420-9063

Funding

Italian Association for Cancer Research grant IG20762Ministry of Education, Universities and Research project N. 2017BMK8JR
6 · The paper itself

Abstract

Current therapy against severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) are based on the use of Remdesivir

Indexed as

COVID-19SARS-CoV-2Antiviral AgentsHumansAntiviral AgentsantiviralsDDX3Xdecoration approachprivileged scaffoldSARS-CoV-2s-triazines

Identifiers

PMID36557962
PMCPMC9782877

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.