Evidence map›Paper›PMID 36558528›Full record

ReviewNutrients2022

Saffron against Neuro-Cognitive Disorders: An Overview of Its Main Bioactive Compounds, Their Metabolic Fate and Potential Mechanisms of Neurological Protection.

Débora Cerdá-Bernad, Leonor Costa, Ana Teresa Serra, Maria Rosário Bronze, Estefanía Valero-Cases, Francisca Pérez-Llamas, María Emilia Candela, Marino B Arnao, Francisco Tomás Barberán, Rocío García Villalba and 2 more

Abstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Therapeutic Effects of Zhilong Huoxue Tongyu Capsule on Oxidative Stress and Neuroprotection in a Rat Model of Intracerebral Hemorrhage.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Frontiers in molecular neuroscience · 2026
    Article
  8. Current pharmaceutical design · 2026
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Journal of biomedical research · 2024
    Article
  14. Saffron (Nutrients · 2024
    Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Débora Cerdá-BernadResearch Group on Quality and Safety, Agro-Food Technology Department, CIAGRO-UMH, Centro de Investigación e Innovación Agroalimentaria y Agroambiental, Miguel Hernández University, 03312 Orihuela, Spain.ORCID 0000-0003-0612-9211
Leonor CostaiBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2781-901 Oeiras, Portugal.
Ana Teresa SerraiBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2781-901 Oeiras, Portugal.ORCID 0000-0002-8618-8299
Maria Rosário BronzeiBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2781-901 Oeiras, Portugal.
Estefanía Valero-CasesResearch Group on Quality and Safety, Agro-Food Technology Department, CIAGRO-UMH, Centro de Investigación e Innovación Agroalimentaria y Agroambiental, Miguel Hernández University, 03312 Orihuela, Spain.ORCID 0000-0002-6082-4410
Francisca Pérez-LlamasDepartment of Physiology, Faculty of Biology, University of Murcia, 30100 Murcia, Spain.
María Emilia CandelaDepartment of Plant Biology (Plant Physiology), Faculty of Biology, University of Murcia, 30100 Murcia, Spain.
Marino B ArnaoDepartment of Plant Biology (Plant Physiology), Faculty of Biology, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0001-8517-6889
Francisco Tomás BarberánResearch Group on Quality, Safety and Bioactivity of Plant Foods, Centro de Edafología y Biología Aplicada del Segura (CEBAS), Spanish National Research Council (CSIC), Campus de Espinardo, 30100 Murcia, Spain.ORCID 0000-0002-0790-1739
Rocío García VillalbaResearch Group on Quality, Safety and Bioactivity of Plant Foods, Centro de Edafología y Biología Aplicada del Segura (CEBAS), Spanish National Research Council (CSIC), Campus de Espinardo, 30100 Murcia, Spain.
María-Teresa García-ConesaResearch Group on Quality, Safety and Bioactivity of Plant Foods, Centro de Edafología y Biología Aplicada del Segura (CEBAS), Spanish National Research Council (CSIC), Campus de Espinardo, 30100 Murcia, Spain.ORCID 0000-0002-4125-853X
María-José FrutosResearch Group on Quality and Safety, Agro-Food Technology Department, CIAGRO-UMH, Centro de Investigación e Innovación Agroalimentaria y Agroambiental, Miguel Hernández University, 03312 Orihuela, Spain.ORCID 0000-0003-0620-5050

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saffron (

Indexed as

Biological ProductsCognitive DysfunctionCrocusNervous System DiseasesHumansPlant ExtractsBiological ProductsPlant Extractsapocarotenoidsbioavailabilitycolon microbiotacrocetincrocinflavonoidsneurological disordersplant by-productssaffron

Identifiers

PMID36558528
PMCPMC9781906

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.