Evidence map›Paper›PMID 36560434›Full record

ReviewVaccines2022

COVID-19 and NSTEMI Outcomes among Hospitalized Patients in the United States and Racial Disparities in Mortality: Insight from National Inpatient Sample Database.

Harris Majeed, Karthik Gangu, Shazib Sagheer, Ishan Garg, Umair Khan, Hina Shuja, Aniesh Bobba, Prabal Chourasia, Rahul Shekhar, Sindhu Reddy Avula and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Long COVID and myocardial ischemia: how aware are we?The international journal of cardiovascular imaging · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Harris MajeedDepartment of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87106, USA.
Karthik GanguDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, KS 66103, USA.
Shazib SagheerDivision of Cardiology, University of New Mexico Health Sciences Center, Albuquerque, NM 87106, USA.
Ishan GargDepartment of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87106, USA.
Umair KhanDepartment of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87106, USA.ORCID 0000-0002-6289-8245
Hina ShujaDepartment of Medicine, Karachi Medical and Dental College, Karachi 74700, Pakistan.
Aniesh BobbaDepartment of Medicine, John H. Stronger Hospital, Cook County, Chicago, IL 60612, USA.
Prabal ChourasiaDivision of Hospital Medicine, Mary Washington Hospital, Fredericksburg, VA 22401, USA.
Rahul ShekharDepartment of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87106, USA.
Sindhu Reddy AvulaDepartment of Interventional Cardiology, Division of Cardiology, University of Kansas, St. Francis Campus, Kansas City, KS 66606, USA.
Abu Baker SheikhDepartment of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87106, USA.ORCID 0000-0003-0503-6961
University of New Mexico · USJohn H. Stroger, Jr. Hospital of Cook County · USKarachi Medical and Dental College · PKMary Washington Hospital · USUniversity of Kansas · USUniversity of Kansas Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has impacted healthcare delivery to patients with non-ST-segment elevation myocardial infraction (NSTEMI). The aim of our retrospective study is to determine the effect of COVID-19 on inpatient NSTEMI outcomes and to investigate whether changes in cardiac care contributed to the observed outcomes. After multivariate adjustment, we found that NSTEMI patients with COVID-19 had a higher rate of inpatient mortality (37.3% vs. 7.3%, adjusted odds ratio: 4.96, 95% CI: 4.6−5.4, p < 0.001), increased length of stay (9.9 days vs. 5.4 days, adjusted LOS: 3.6 days longer, p < 0.001), and a higher cost of hospitalization (150,000 USD vs. 110,000 USD, inflation-adjusted cost of hospitalization: 36,000 USD higher, p < 0.001) in comparison to NSTEMI patients without COVID-19, despite a lower burden of pre-existing cardiac comorbidity. NSTEMI patients with COVID-19 also received less invasive cardiac procedures (coronary angiography: 8.7% vs. 50.3%, p < 0.001; PCI: 4.8% vs. 29%, p < 0.001; and CABG: 0.7% vs. 6.2%, p < 0.001). In our study, we observed increased mortality and in-hospital complications to be a combined effect of COVID-19 infection and myocardial inflammation as a result of cytokine storm, prothrombic state, oxygen supply/demand imbalance and alterations in healthcare delivery from January to December 2020.

Indexed as

COVID-19mortalitynational inpatient sampleNSTEMIUnited States

Identifiers

PMID36560434
PMCPMC9780864
OpenAlexW4310211590

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.