Evidence map›Paper›PMID 36560726›Full record

ArticleViruses2022

Diarrhea Is a Hallmark of Inflammation in Pediatric COVID-19.

Marco Poeta, Francesco Nunziata, Margherita Del Bene, Francesca Morlino, Alessia Salatto, Sara Maria Scarano, Valentina Cioffi, Michele Amitrano, Eugenia Bruzzese, Alfredo Guarino and 1 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Acute Infectious Diarrhea.Advances in experimental medicine and biology · 2024
    Review
  7. Applied and environmental microbiology · 2023
    Article
  8. Postbiotic Preparation ofAntioxidants (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Marco PoetaDepartment of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-7515-1394
Francesco NunziataDepartment of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, 80131 Naples, Italy.
Margherita Del BeneDepartment of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, 80131 Naples, Italy.
Francesca MorlinoDepartment of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-8205-3901
Alessia SalattoDepartment of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, 80131 Naples, Italy.
Sara Maria ScaranoDepartment of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, 80131 Naples, Italy.
Valentina CioffiDepartment of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, 80131 Naples, Italy.
Michele AmitranoDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Eugenia BruzzeseDepartment of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, 80131 Naples, Italy.
Alfredo GuarinoDepartment of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, 80131 Naples, Italy.
Andrea Lo VecchioDepartment of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-4181-6842
University of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a pathogen with enteric tropism. We compared the clinical, biochemical and radiological features of children hospitalized for acute SARS-CoV-2 infection, classified in two groups based on the presence of diarrhea. Logistic regression analyses were used to investigate the variables associated with diarrhea. Overall, 407 children were included in the study (226 males, 55.5%, mean age 3.9 ± 5.0 years), of whom 77 (18.9%) presented with diarrhea, which was mild in most cases. Diarrhea prevalence was higher during the Alpha (23.6%) and Delta waves (21.9%), and in children aged 5-11 y (23.8%). Other gastrointestinal symptoms were most commonly reported in children with diarrhea (

Indexed as

COVID-19ChildChild, PreschoolDiarrheaHumansInflammationMaleSARS-CoV-2Systemic Inflammatory Response SyndromechildrenCOVID-19diarrheagastrointestinalgutSARS-CoV-2

Identifiers

PMID36560726
PMCPMC9783993
OpenAlexW4311714475

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.