Evidence map›Paper›PMID 36560787›Full record

ArticleViruses2022

Exploration of Potent Antiviral Phytomedicines from Lauraceae Family Plants against SARS-CoV-2 Main Protease.

Himashree Bora, Madhu Kamle, Hesham Hassan, Ahmed Al-Emam, Sidharth Chopra, Nikhil Kirtipal, Shiv Bharadwaj, Pradeep Kumar

Abstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Himashree BoraApplied Microbiology Laboratory, North Easter Regional Institute of Science and Technology, Nirjuli 791109, Arunachal Pradesh, India.ORCID 0000-0002-0366-2910
Madhu KamleApplied Microbiology Laboratory, North Easter Regional Institute of Science and Technology, Nirjuli 791109, Arunachal Pradesh, India.ORCID 0000-0002-7764-1418
Hesham HassanDepartment of Pathology, College of Medicine, King Khalid University, Abha 62529, Saudi Arabia.
Ahmed Al-EmamDepartment of Pathology, College of Medicine, King Khalid University, Abha 62529, Saudi Arabia.
Sidharth ChopraDivision of Molecular Microbiology and Immunology, CSIR-Central Drug Research Institute, Sector 10, Janakipuram Extension, Sitapur Road, Lucknow 226031, Uttar Pradesh, India.
Nikhil KirtipalSchool of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Republic of Korea.ORCID 0000-0001-7422-3408
Shiv BharadwajDepartment of Biotechnology, Institute of Biotechnology, College of Life and Applied Sciences, Yeungnam University, 280 Daehak-Ro, Gyeongsan 38541, Republic of Korea.ORCID 0000-0003-2832-8617
Pradeep KumarApplied Microbiology Laboratory, North Easter Regional Institute of Science and Technology, Nirjuli 791109, Arunachal Pradesh, India.ORCID 0000-0002-0892-5425

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new Coronaviridae strain, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), emerged from Wuhan city of China and caused one of the substantial global health calamities in December 2019. Even though several vaccines and drugs have been developed worldwide since COVID-19, a cost-effective drug with the least side effects is still unavailable. Currently, plant-derived compounds are mostly preferred to develop antiviral therapeutics due to its less toxicity, easy access, and cost-effective characteristics. Therefore, in this study, 124 phytochemical compounds from plants of Lauraceae family with medicinal properties were virtually screened against SARS-CoV-2 M

Indexed as

Antiviral AgentsCOVID-19Coronavirus 3C ProteasesHumansMolecular Docking SimulationMolecular Dynamics SimulationProtease InhibitorsSARS-CoV-23C-like proteinase, SARS-CoV-2Antiviral AgentsCoronavirus 3C ProteasesProtease Inhibitorscassameridinecassythicinedockinglaetaninelitseferinemain proteaseMD simulationsSARS-CoV-2

Identifiers

PMID36560787
PMCPMC9785681

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.