ReviewAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2023
Penicillin allergy delabeling: Opportunities for implementation and dissemination.
Review in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Quality and Consistency of Penicillin Allergy Delabelling Guidelines: A Systematic Review.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026Pooled it
- Penicillin allergies and community antibiotic prescriptions: A secondary analysis of prescribing choices in six family medicine clinics in southern Ontario, 2018-2019.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2026Article
- PEN-DEL: implementing penicillin allergy de-labeling in hospitalized older adults - a quality improvement initiative.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Deficiencies in the Assessment of Penicillin Allergy in Hospitalized Children in Hawai'i, 2021-2023.Hawai'i journal of health & social welfare · 2026Article
- Outpatient penicillin allergy de-labeling in primary care-whom to target.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Evaluation of the Allergy Fact Checker, a clinical decision support system for non-invasive beta-lactam delabeling: a mixed-methods study.NPJ digital medicine · 2025Article
- Article
- Assessment of penicillin allergy evaluation practices among clinicians in China: a nationwide cross-sectional survey.BMJ open · 2025Article
- Healthcare professionals' experiences of de-labelling erroneous penicillin allergy records in general practice: a qualitative study.BJGP open · 2025Article
- Development of a single-step lateral flow immunoassay for penicillin G allergy screening.Mikrochimica acta · 2025Article
- Penicillin allergy delabeling in long-term care facilities: if not now, then when?Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Mandatory linking of penicillin allergy "safety alert" with beta-lactam medication history: correcting the automated inaccuracy of penicillin allergy labeling and beta-lactam antibiotic avoidance.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Proactive Deep Learning-Facilitated Inpatient Penicillin Allergy Delabelling: An Implementation Study.International archives of allergy and immunology · 2025Article
- Health disparities investigated in a primary care penicillin allergy removal pathway.Allergy and asthma proceedings · 2025Article
- Leveraging implementation science theories to develop and expand the use of a penicillin allergy de-labeling intervention.BMC health services research · 2024Article
- Narrative review of recent developments and the future of penicillin allergy de-labelling by non-allergists.npj antimicrobials and resistance · 2024Review
- Long-Term Outcomes Associated With β-Lactam Allergies.JAMA network open · 2024Article
- Barriers to penicillin allergy de-labeling in the inpatient and outpatient settings: a qualitative study.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023Article
- Delabelling multiple antibiotic allergy: Practical issues.Frontiers in allergy · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Although existing as a safety measure to prevent iatrogenic harm, unconfirmed penicillin allergy labels have a negative impact on personal and public health. One downstream effect of unconfirmed penicillin allergy is the continued emergence and transmission of resistant bacteria and their associated health care costs. Recognizing the consequences of inaccurate penicillin allergy labels, professional and public health organizations have started promoting the adoption of proactive penicillin allergy evaluations, with the ultimate goal of removing the penicillin allergy label when the allergy is disproved, also known as penicillin allergy "delabeling." A penicillin allergy evaluation includes a comprehensive allergy history often followed by drug challenge, sometimes with preceding skin testing. Currently, penicillin allergy delabeling is largely carried out by allergy specialists in outpatient settings. Penicillin allergy delabeling is performed on inpatients, albeit rarely, often at the time of need, as a point-of-care procedure. Access to penicillin allergy evaluation services is limited. Recent studies demonstrate the feasibility of expanding penicillin allergy evaluations and delabeling to internists, pediatricians, emergency medicine physicians, infectious diseases specialists, and clinical pharmacists. However, reducing the impact of mislabeled penicillin allergy will require comprehensive efforts and new investments. In this review, we summarize the current practices of penicillin allergy delabeling and discuss expansion opportunities for penicillin allergy delabeling as quality improvement.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.