Evidence map›Paper›PMID 36564645›Full record

ArticleFunctional & integrative genomics2022

An effect of large-scale deletions and duplications on transcript expression.

Magda Mielczarek, Magdalena Frąszczak, Anna E Zielak-Steciwko, Błażej Nowak, Bartłomiej Hofman, Jagoda Pierścińska, Wojciech Kruszyński, Joanna Szyda

Abstract read
In one paragraph

Article in Functional & integrative genomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Magda MielczarekWroclaw University of Environmental and Life Sciences, Kozuchowska 7, 51-631, Wroclaw, Poland. magda.mielczarek@upwr.edu.pl.ORCID http://orcid.org/0000-0002-1086-9119
Magdalena FrąszczakWroclaw University of Environmental and Life Sciences, Kozuchowska 7, 51-631, Wroclaw, Poland.ORCID http://orcid.org/0000-0002-8012-4980
Anna E Zielak-SteciwkoWroclaw University of Environmental and Life Sciences, Kozuchowska 7, 51-631, Wroclaw, Poland.ORCID http://orcid.org/0000-0003-0554-3453
Błażej NowakWroclaw University of Environmental and Life Sciences, Kozuchowska 7, 51-631, Wroclaw, Poland.ORCID http://orcid.org/0000-0003-0627-0047
Bartłomiej HofmanWroclaw University of Environmental and Life Sciences, Kozuchowska 7, 51-631, Wroclaw, Poland.ORCID http://orcid.org/0000-0002-1188-8186
Jagoda PierścińskaWroclaw University of Environmental and Life Sciences, Kozuchowska 7, 51-631, Wroclaw, Poland.ORCID http://orcid.org/0000-0003-2550-5606
Wojciech KruszyńskiWroclaw University of Environmental and Life Sciences, Kozuchowska 7, 51-631, Wroclaw, Poland.ORCID http://orcid.org/0000-0002-3289-100X
Joanna SzydaWroclaw University of Environmental and Life Sciences, Kozuchowska 7, 51-631, Wroclaw, Poland.ORCID http://orcid.org/0000-0001-9688-0193

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since copy number variants (CNVs) have been recognized as an important source of genetic and transcriptomic variation, we aimed to characterize the impact of CNVs located within coding, intergenic, upstream, and downstream gene regions on the expression of transcripts. Regions in which deletions occurred most often were introns, while duplications in coding regions. The transcript expression was lower for deleted coding (P = 0.008) and intronic regions (P = 1.355 × 10

Indexed as

DNA Copy Number VariationsGenomeAnimalsExonsGenomicsIntronsCNVsDNA-seqRNA-seqSus scrofaTranscript expression

Identifiers

PMID36564645
PMCPMC9789009

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.