Evidence map›Paper›PMID 36567907›Full record

ArticleBioMed research international2022

Short-Term

Bijorn Omar Balzamino, Lucia Dinice, Andrea Cacciamani, Agnese Re, Fabio Scarinci, Luca Bruno, Pamela Cosimi, Alessandra Micera

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Bijorn Omar BalzaminoResearch Laboratories in Ophthalmology, IRCCS-Fondazione Bietti, Rome, Italy.ORCID https://orcid.org/0000-0002-2254-1647
Lucia DiniceResearch Laboratories in Ophthalmology, IRCCS-Fondazione Bietti, Rome, Italy.
Andrea CacciamaniRetinal Unit, IRCCS-Fondazione Bietti, Rome, Italy.
Agnese ReUniversità Cattolica del Sacro Cuore, Rome, Italy.
Fabio ScarinciRetinal Unit, IRCCS-Fondazione Bietti, Rome, Italy.
Luca BrunoResearch Laboratories in Ophthalmology, IRCCS-Fondazione Bietti, Rome, Italy.
Pamela CosimiRetinal Unit, IRCCS-Fondazione Bietti, Rome, Italy.
Alessandra MiceraResearch Laboratories in Ophthalmology, IRCCS-Fondazione Bietti, Rome, Italy.ORCID https://orcid.org/0000-0002-9375-6071
Fondazione G.B. Bietti · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A plethora of inflammatory, angiogenic, and tissue remodeling factors has been reported in idiopathic epiretinal membranes (ERMs). Herein we focused on the expression of a few mediators (oxidative, inflammatory, and angiogenic/vascular factors) by means of short-term vitreal cell cultures and biomolecular analysis. Methods: Thirty-nine (39) ERMs and vitreal samples were collected at the time of vitreoretinal surgery and biomolecular analyses were performed in clear vitreous, vitreal cell pellets, and ERMs. ROS products and iNOS were investigated in adherent vitreal cells and/or ERMs, and iNOS, VEGF, Ang-2, IFN Results: The higher ROS production was observed in vitreal cells at stage 4, and iNOS was found in ERMs and increased in the vitreous as early as at stage 3. Both Conclusions: ROS production was strictly associated with

Indexed as

Epiretinal MembraneOxidative StressReactive Oxygen SpeciesHumansInterleukin-18Kelch-Like ECH-Associated Protein 1NADPH Oxidase 4NF-E2-Related Factor 2Nitric Oxide Synthase Type IITranscription Factor RelAVascular Endothelial Growth Factor AInterleukin-18Kelch-Like ECH-Associated Protein 1NADPH Oxidase 4NFE2L2 protein, humanNF-E2-Related Factor 2Nitric Oxide Synthase Type IINOS2 protein, humanNOX4 protein, humanReactive Oxygen SpeciesRELA protein, humanTranscription Factor RelAVascular Endothelial Growth Factor A

Identifiers

PMID36567907
PMCPMC9788888
OpenAlexW4311690279

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.