Evidence map›Paper›PMID 36568688›Full record

ArticleReview journal of autism and developmental disorders2022

Electrophysiological Studies of Reception of Facial Communication in Autism Spectrum Disorder and Schizophrenia.

Emily J Levy, Jennifer Foss-Feig, Emily L Isenstein, Vinod Srihari, Alan Anticevic, Adam J Naples, James C McPartland

Open access · greenAbstract read
In one paragraph

Article in Review journal of autism and developmental disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Emily J LevyBiology Department, Duke University.
Jennifer Foss-FeigDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai.
Emily L IsensteinMedical Center, University of Rochester.
Vinod SrihariDepartment of Psychiatry, Yale University School of Medicine.
Alan AnticevicDepartment of Psychiatry, Yale University School of Medicine.
Adam J NaplesYale Child Study Center, Yale University School of Medicine.
James C McPartlandDepartment of Psychology, Yale University.
Yale University · USDuke University · USIcahn School of Medicine at Mount Sinai · USUniversity of Rochester Medical Center · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
The Autism Biomarkers Consortium for Clinical TrialsU19MH108206 · NIMH · YALE UNIVERSITY · PI MCPARTLAND, JAMES CHARLES · 2015 to 2024
$68.8M
STEP-ED:Reducing Duration of Untreated Psychosis and its Impact in the U.S.R01MH103831 · NIMH · YALE UNIVERSITY · PI SRIHARI, VINOD H. · 2013 to 2017
$3.9M
Characterizing Cognitive Impairment in Schizophrenia via Computational Modeling aDP5OD012109 · OD · YALE UNIVERSITY · PI ANTICEVIC, ALAN · 2012 to 2016
$1.8M
Neural markers of shared gaze during simulated social interactions in ASDR01MH100173 · NIMH · YALE UNIVERSITY · PI MCPARTLAND, JAMES CHARLES · 2013 to 2015
$1.3M
Specialized Treatment Early in Psychosis (STEP): A community health center basedRC1MH088971 · NIMH · YALE UNIVERSITY · PI SRIHARI, VINOD H. · 2009 to 2010
$750k
Developmental Social Neuroscience in Infants At-Risk for AutismK23MH086785 · NIMH · YALE UNIVERSITY · PI MCPARTLAND, JAMES CHARLES · 2010 to 2013
$725k
Multimodel Assessment of Social Process Systems across Neurodevelopmental DisordersR01MH107426 · NIMH · YALE UNIVERSITY · PI MCPARTLAND, JAMES CHARLES, SRIHARI, VINOD H. · 2015 to 2017
$651k
Connectivity in social brain systems in autismR21MH091309 · NIMH · YALE UNIVERSITY · PI MCPARTLAND, JAMES CHARLES · 2010 to 2011
$453k
NCATS NIH HHS UL1 TR001863NIH HHS DP5 OD012109NIMH NIH HHS K23 MH086785NIMH NIH HHS R01 MH100173NIMH NIH HHS R01 MH103831NIMH NIH HHS R01 MH107426NIMH NIH HHS R21 MH091309NIMH NIH HHS RC1 MH088971NIMH NIH HHS U19 MH108206
6 · The paper itself

Abstract

Autism spectrum disorder (ASD) and schizophrenia spectrum disorders (SZ) are characterized by difficulty with social cognition and atypical reception of facial communication - a key area in the Research Domain Criteria framework. To identify areas of overlap and dissociation between ASD and SZ, we review studies of event-related potentials (ERP) to faces across ASD and SZ populations, focusing on ERPs implicated in social perception: P100, N170, N250, and P300. There were many inconsistent findings across studies; however, replication was strongest for delayed N170 latency in ASD and attenuated N170 amplitude in SZ. These results highlight the challenges of replicating research findings in heterogeneous clinical populations and the need for transdiagnostic research that continuously quantifies behavior and neural activity across neurodevelopmental disorders.

Indexed as

autism spectrum disorderelectrophysiologyemotionfaceResearch Domain Criteriaschizophrenia

Identifiers

PMID36568688
PMCPMC9783109
OpenAlexW3177314280

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.