Evidence map›Paper›PMID 36570575›Full record

ArticleThe Saudi dental journal2022

The influence of periodontal status and serum biomarkers on salivary leptin levels in systemic lupus erythematosus patients.

Leslie A da Silva, Consuelo P C Marques, Izabel C V de Oliveira, Mayra M Franco, Vandilson P Rodrigues, Bruno B Benatti

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Saudi dental journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Leslie A da SilvaDentistry Graduate Program, Federal University of Maranhão, São Luís, Brazil.
Consuelo P C MarquesDentistry Graduate Program, Federal University of Maranhão, São Luís, Brazil.
Izabel C V de OliveiraDentistry Graduate Program, Federal University of Maranhão, São Luís, Brazil.
Mayra M FrancoDentistry Graduate Program, Federal University of Maranhão, São Luís, Brazil.
Vandilson P RodriguesDentistry Graduate Program, Federal University of Maranhão, São Luís, Brazil.
Bruno B BenattiDentistry Graduate Program, Federal University of Maranhão, São Luís, Brazil.
Universidade Federal do Maranhão · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to investigate the influence of periodontal status, clinical data, and serum markers on salivary leptin levels in patients with systemic lupus erythematosus (SLE). Methods: A case-control study was conducted with 38 patients with SLE and 29 healthy controls. Periodontal data included periodontal probing depth (PPD), clinical attachment level (CAL), and gingival bleeding on probing (BOP). Stimulated saliva samples were collected to analyze salivary leptin levels. Clinical and serum data were collected from the SLE group. Statistical analysis included the Results: The SLE group had a lower salivary leptin level than the control group (P = 0.002). The model revealed that SLE had an inverse and independent effect on salivary leptin (standardized estimate =  - 0.289, P = 0.023). Moreover, salivary leptin level negatively correlated with the serum levels of triglyceride, creatinine, and leukocytes, positively correlated with the serum total cholesterol, but was not significantly correlated with the periodontal status. Conclusion: These findings suggest that patients with SLE have a lower salivary leptin level. In addition, the level of salivary leptin does not appear to be related to periodontal status in patients with SLE.

Indexed as

BMI, body mass indexCAL, clinical attachment levelCFI, comparative fit indexGBI, gingival bleeding indexGOT, glutamic oxaloacetic transaminaseGPT, glutamate-pyruvate transaminaseLeptinPeriodontal diseasesPPD, periodontal probing depthRMSEA, root mean square error of approximationSalivaSEM, structural equation modelSLE, systemic lupus erythematosusSRMR, standardized root mean square residualSystemic lupus erythematosusTG, triglyceridesTLI, Tucker-Lewis index

Identifiers

PMID36570575
PMCPMC9767834
OpenAlexW4309564103

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.