Evidence mapPaperPMID 36571659Full record

ReviewJournal of thrombosis and thrombolysis2023

Role of cerebral microbleeds in acute ischemic stroke and atrial fibrillation.

Meng Wang, Yuyuan Yang, Moxin Luan, Yajuan Wang, Meixiang Zhong, Lulu Xu, Xueping Zheng

Abstract readReview
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In one paragraph

Review in Journal of thrombosis and thrombolysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Meng WangDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, No.16 Jiangsu Road, Qingdao, 266001, Shandong, China.
Yuyuan YangDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, No.16 Jiangsu Road, Qingdao, 266001, Shandong, China.
Moxin LuanDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, No.16 Jiangsu Road, Qingdao, 266001, Shandong, China.
Yajuan WangDepartment of Geriatric Medicine, The Qingdao Eighth People's Hospital, Qingdao, China.
Meixiang ZhongDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, No.16 Jiangsu Road, Qingdao, 266001, Shandong, China.
Lulu XuDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, No.16 Jiangsu Road, Qingdao, 266001, Shandong, China.
Xueping ZhengDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, No.16 Jiangsu Road, Qingdao, 266001, Shandong, China. simplexueping@163.com.ORCID http://orcid.org/0000-0003-2763-8509
Qingdao University · CNQingdao Eighth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral microbleeds (CMBs) are commonly detected in the brains of patients with acute ischemic stroke (AIS). With the development of neuroimaging, clinicians are paying more attention to the presence of CMBs. CMBs were found to significantly increase the risk of intracranial hemorrhagic transformation and hemorrhage in patients with AIS, especially in patients with concurrent atrial fibrillation (AF). Additionally, the presence of CMBs is thought to be a symbol of a high risk of recurrent ischemic stroke (IS). A few researchers have found that the presence of CMBs has no significant effect on the prognosis of patients with AIS. Therefore, the current views on the role of CMBs in the prognoses of patients with IS are controversial. The use of anticoagulants and other drugs has also become a dilemma due to the special influence of CMBs on the prognosis of these patients. Due to the large number of patients with AF and CMBs, many studies have been conducted on the effects of CMBs on these patients and subsequent pharmacological treatments. However, at present, there are no relevant guidelines to guide the secondary preventive treatment of patients with stroke, CMBs, and AF. In this paper, we summarized the role of CMBs in AIS combined with AF and relevant preventive measures against the recurrence of stroke and the occurrence of intracerebral hemorrhage to help clarify the specifics of drug therapies for this group of patients.

Indexed as

Atrial FibrillationBrain IschemiaIschemic StrokeStrokeCerebral HemorrhageHumansMagnetic Resonance ImagingRisk FactorsAntithrombotic treatmentAtrial fibrillationCerebral microbleedsIschemic strokeSecondary prevention

Identifiers

PMID36571659
OpenAlexW4312196458

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.