Evidence map›Paper›PMID 36580919›Full record

ArticleImmunity2023

Small intestine and colon tissue-resident memory CD8

Yun Hsuan Lin, Han G Duong, Abigail E Limary, Eleanor S Kim, Paul Hsu, Shefali A Patel, William H Wong, Cynthia S Indralingam, Yi Chia Liu, Priscilla Yao and 11 more

Open access · greenAbstract read
In one paragraph

Article in Immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Efficacy of Advanced Therapies in Achieving Remission by Disease Location in Crohn's Disease: A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Pooled it
  2. Article
  3. CD8MedComm · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. A CCL5Cell & bioscience · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Exploration (Beijing, China) · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 1 institution in 1 country.

Yun Hsuan LinDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Han G DuongDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Abigail E LimaryDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Eleanor S KimDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Paul HsuDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Shefali A PatelDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
William H WongDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Cynthia S IndralingamDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Yi Chia LiuDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Priscilla YaoDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Natalie R ChiangDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Sara A VandenburghDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Taylor R AndersonDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Jocelyn G OlveraDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Amir FerryDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.
Kennidy K TakeharaDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.
Wenhao JinDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Matthew S TsaiDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Gene W YeoDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Ananda W GoldrathDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.
John T ChangDepartment of Medicine, University of California San Diego, La Jolla, CA 92093, USA; Department of Medicine, Jennifer Moreno Department of Veteran Affairs Medical Center, San Diego, CA 92161, USA. Electronic address: changj@ucsd.edu.
University of California San Diego · US

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DIANE M SIMEONE · 1985 to 2026
$124.9M
Functional RNA elements in the human genomeR01HG004659 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Kevin Daniel Corbett, Eugene Wei-Ming Yeo · 2008 to 2026
$12.4M
San Diego Digestive Diseases Research CenterP30DK120515 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Bernd G. Schnabl · 2019 to 2026
$10.8M
Single-Cell Transcriptomic and Epigenetics CoreP01AI132122 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZUNIGA, ELINA I · 2018 to 2022
$9.8M
Training Grant in GastroenterologyT32DK007202 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GHOSH, PRADIPTA · 1985 to 2022
$7.7M
Rheumatic Diseases Research Training GrantT32AR064194 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GARY S FIRESTEIN, Monica Guma · 2013 to 2026
$3.8M
Using single-cell RNA-seq to interrogate host immunity to pathogensR01AI123202 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHANG, JOHN T, YEO, EUGENE WEI-MING · 2016 to 2020
$3.1M
Role of proteasome activity in adaptive immunityR01AI129973 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHANG, JOHN T · 2018 to 2022
$2.2M
Illumina NovaSeq 6000 Sequencing SystemS10OD026929 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEPSEN, KRISTEN LYNN · 2019 to 2019
$600k
Transcriptional regulation of T cell immunityI01BX005106 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, JOHN T · 2021 to 2024
–
T cell subsets in inflammatory bowel diseaseI01CX002396 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI John T Chang · 2022 to 2026
–
BLRD VA I01 BX005106CSRD VA I01 CX002396NCI NIH HHS P30 CA023100NHGRI NIH HHS R01 HG004659NIAID NIH HHS P01 AI132122NIAID NIH HHS R01 AI123202NIAID NIH HHS R01 AI129973NIAMS NIH HHS T32 AR064194NIDDK NIH HHS P30 DK120515NIDDK NIH HHS T32 DK007202NIH HHS S10 OD026929
6 · The paper itself

Abstract

Tissue-resident memory CD8

Indexed as

CD8-Positive T-LymphocytesMemory T CellsColonImmunologic MemoryIntestine, SmallcolonEomessingle-cell ATAC-sequencingsingle-cell RNA-sequencingsmall intestinetissue-resident memory CD8(+) T cells

Identifiers

PMID36580919
PMCPMC9904390
OpenAlexW4313312677

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.