Evidence map›Paper›PMID 36583064›Full record

ArticleDisease markers2022

Actin-Binding LIM 1 (ABLIM1) Inhibits Glioblastoma Progression and Serves as a Novel Prognostic Biomarker.

Danping Liu, Xiaoping Wang, Ying Liu, Chunliu Li, Zhen Zhang, Peng Lv

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Upregulation ofGenes · 2024
    Article
  6. Article
  7. miR-2467-3p/ABLIM1 Axis Mediates the Formation and Progression of Deep Vein Thrombosis by Regulating Inflammation and Oxidative Stress.The International journal of angiology : official publication of the International College of Angiology, Inc · 2024
    Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Danping LiuDepartment of Neurology, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, China.
Xiaoping WangDepartment of Neurology, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, China.
Ying LiuDepartment of Neurology, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, China.
Chunliu LiDepartment of Clinical Laboratory, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, China.
Zhen ZhangDepartment of Neurology, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, China.
Peng LvDepartment of Quality Control Division, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, China.ORCID https://orcid.org/0000-0003-3239-2179
Yuhuangding Hospital · CNBinzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Glioma is the most prevalent malignant brain tumor in adult humans, and glioblastoma (GBM) is the most malignant type. The actin-binding LIM 1 (ABLIM1) protein can modulate actin polymerization, which is essential for the cell proliferation and migration. We aim to investigate ABLIM1 expression, function, and clinical significance in GBM. Methods: The Results: Conclusion: ABLIM1 plays antitumor roles in GBM progression and could be served as a novel biomarker to help predict GBM prognosis.

Indexed as

Brain NeoplasmsGlioblastomaGliomaLIM Domain ProteinsMicrofilament ProteinsActinsAdultAnimalsCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansMiceMice, NudePrognosisRNA, MessengerABLIM1 protein, humanActinsLIM Domain ProteinsMicrofilament ProteinsRNA, Messenger

Identifiers

PMID36583064
PMCPMC9794427
OpenAlexW4313450337

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.