Evidence map›Paper›PMID 36588944›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Superporous acrylic acid and HPMC hydrogels of mefenamic acid: Formulation, characterization and optimization by central composite design.

Hafeez Ullah Khan, Samar Aziz, Safirah Maheen, Ikramullah Khan, Mehwish Andleeb, Hina Younis, Sajjad Haider, Adnan Haider, Muhammad Saeed Akhtar, Syed Salman Shafqat

Open access · goldAbstract read
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In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Hafeez Ullah KhanDepartment of Pharmaceutics, University of Sargodha, Sargodha, Pakistan.
Samar AzizDepartment of Pharmaceutics, University of Sargodha, Sargodha, Pakistan.
Safirah MaheenDepartment of Pharmaceutics, University of Sargodha, Sargodha, Pakistan.
Ikramullah KhanDepartment of Pharmaceutics, Faculty of Pharmaceutical Sciences, Government College University Faisalabad, Faisalabad, Pakistan.
Mehwish AndleebDepartment of Pharmaceutics, University of Sargodha, Sargodha, Pakistan.
Hina YounisDepartment of Pharmaceutics, University of Sargodha, Sargodha, Pakistan.
Sajjad HaiderDepartment of Chemical Engineering, College of Engineering, King Saud University, Riyadh, Saudi Arabia.
Adnan HaiderDepartment of Biological Sciences, National University of Medical Sciences, Rawalpindi, Pakistan.
Muhammad Saeed AkhtarSchool of Chemical Engineering, Yeungnam University, Gyeongsan, South Korea.
Syed Salman ShafqatDepartment of Chemistry, Division of Science and Technology, University of Education, Lahore, Pakistan.
University of Sargodha · PKGovernment College University, Faisalabad · PKKing Saud University · SANational University of Medical Sciences · PKUniversity of Okara · PKYeungnam University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the study was to devise the superporous hydrogels (SPHs) of mefenamic acid (MA) to acquire the sustained action of the MA in the body. The superporous hydrogels of mefenamic acid were formulated by employing the gas blowing method. The central composite rotatable design (CCRD) was applied to optimize the effect of independent formulation factors like acrylic acid (AC), HPMC and glycerol (GLY) over dependent variables like porosity, viscosity, drug content and swelling ratio of superporous hydrogels in water, phosphate buffer (pH 6.8) and in 0.1N HCl (pH 1.2). A number of characteristics such as void fraction, surface morphology by Scanning electron microscopy (SEM) and

Indexed as

acrylic acidanalgesiccentral composite rotatable designgas blowing methodHPMCmefenamic acidsuperporous hydrogels

Identifiers

PMID36588944
PMCPMC9797584
OpenAlexW4311505206

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.