ArticleThe journal of applied laboratory medicine2023
Vitamin C Status of US Adults Assessed as Part of the National Health and Nutrition Examination Survey Remained Unchanged between 2003-2006 and 2017-2018.
Article in The journal of applied laboratory medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Contemporary Scurvy in Vulnerable Populations in High-Income Countries: A Systematic Review and Multilevel Meta-Analysis.Nutrients · 2026Pooled it
- Relationship Between Hypovitaminosis C, Obesity, and Features of Metabolic Syndrome-A Narrative Review.Nutrition reviews · 2026Review
- The Prevalence of Nutritional Imbalances in the US Population Over Time: Biomarker Data from the Cross-Sectional National Health and Nutrition Examination Survey (NHANES 1999-2000 through August 2021-August 2023).Current developments in nutrition · 2026Article
- Predictors of Vitamin C Status in National Health and Nutrition Examination Survey 2017-2018: The Effect of Body Weight and Body Mass Index in a Multiple Fractional Polynomial Analysis.The Journal of nutrition · 2025Article
- Relationship between urinary iodine concentration and all-cause mortality in individuals with diabetes: An analysis of National Health and Nutrition Examination Survey 2005 - 2018.Hormones (Athens, Greece) · 2025Article
- The Community Prevalence of Vitamin C Deficiency and Inadequacy-How Does Australia Compare With Other Nations? A Scoping Review.Health science reports · 2025Review
- Vitamin C Transport Deficiency Alters Striatal Dopamine Gene Expression and Metabolism in YAC128 Huntington Disease Mice.Genes, brain, and behavior · 2025Article
- The Prevalence, Risk Factors, and Clinical Outcomes of Vitamin C Deficiency in Adult Hospitalised Patients: A Retrospective Observational Study.Nutrients · 2025Observational
- Relationship between stroke and estimated glucose disposal rate: results from two prospective cohort studies.Lipids in health and disease · 2024Article
- Nutritional Strategies for Chronic Craniofacial Pain and Temporomandibular Disorders: Current Clinical and Preclinical Insights.Nutrients · 2024Review
- Molecular Pharmacology of Vitamin C and Relevance to Health and Obesity-A Narrative Review.International journal of molecular sciences · 2024Review
- A Systematized Review of the Relationship Between Obesity and Vitamin C Requirements.Current developments in nutrition · 2024Review
- Factors Affecting the Vitamin C Dose-Concentration Relationship: Implications for Global Vitamin C Dietary Recommendations.Nutrients · 2023Article
- Does Aging Have an Impact on Vitamin C Status and Requirements? A Scoping Review of Comparative Studies of Aging and Institutionalisation.Nutrients · 2023Article
- Does Aging Affect Vitamin C Status Relative to Intake? Findings from NHANES 2017-2018.Nutrients · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundWe compared serum vitamin C (VIC) status of the adult (≥20 y) US population in the National Health and Nutrition Examination Survey (NHANES) 2017-2018 with combined data from 2003-2004 and 2005-2006.
methodsVIC was measured using HPLC with electrochemical detection. Mean data were stratified by age, sex, race/Hispanic origin, income, body mass index, dietary intake, supplement use, and smoking status. Prevalence of VIC deficiency (<11.4 μmol/L) was calculated.
resultsIn NHANES 2017-2018, the mean VIC was 8 μmol/L higher in people ≥60 y compared with those 20-59 y of age, 10 μmol/L lower in men vs women, 8 μmol/L lower in low vs high income, 11 μmol/L lower in obese vs healthy weight, and 15 μmol/L lower in smokers vs nonsmokers. Differences in mean VIC across race/Hispanic origin groups ranged from 2 to 7 μmol/L. Mean VIC was 27 μmol/L higher with vitamin C-containing supplement use and positively associated (Spearman ρ = 0.33; P < 0.0001) with increasing dietary intake. The associations between mean VIC and the investigated covariates were generally consistent and the prevalence of deficiency was not significantly different between survey periods (6.8% vs 7.0%; P = 0.83). However, a few subgroups had double the risk. We found no significant survey differences in mean VIC (51.2 vs 54.0 μmol/L; P = 0.09).
conclusionsOverall VIC status of the US adult population has remained stable since last assessed in the NHANES 2005-2006 survey. Vitamin C deficiency remained high for those with low dietary intake and who smoke.
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